1. A prodrug strategy for the oral delivery of a poorly soluble HCV NS5B thumb pocket 1 polymerase inhibitor using self-emulsifying drug delivery systems (SEDDS). Issue 2 (15th January 2015) Authors: Beaulieu, Pierre L.; De Marte, Josie; Garneau, Michel; Luo, Laibin; Stammers, Timothy; Telang, Chitra; Wernic, Dominik; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 2(2015) Page Start: 210 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. A prodrug strategy for the oral delivery of a poorly soluble HCV NS5B thumb pocket 1 polymerase inhibitor using self-emulsifying drug delivery systems (SEDDS). Issue 2 (15th January 2015) Authors: Beaulieu, Pierre L.; De Marte, Josie; Garneau, Michel; Luo, Laibin; Stammers, Timothy; Telang, Chitra; Wernic, Dominik; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 2(2015) Page Start: 210 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 1: Mitigating the genotoxic liability of an aniline metabolite. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Duplessis, Martin; Gagnon, Alexandre; Garneau, Michel; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1135 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 1: Mitigating the genotoxic liability of an aniline metabolite. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Duplessis, Martin; Gagnon, Alexandre; Garneau, Michel; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1135 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Deon, Dan; Duplessis, Martin; Fazal, Gulrez; Gagnon, Alexandre; Garneau, Michel; LaPlante, Steven; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1140 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Deon, Dan; Duplessis, Martin; Fazal, Gulrez; Gagnon, Alexandre; Garneau, Michel; LaPlante, Steven; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1140 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗