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Author/Creator Spergel, Steven H.

1. Discovery and structure-based design of 4, 6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Issue 21 (1st November 2017)

Authors:
Bhide, Rajeev S.; Keon, Alec; Weigelt, Carolyn; Sack, John S.; Schmidt, Robert J.; Lin, Shuqun; Xiao, Hai-Yun; Spergel, Steven H.; Kempson, James; Pitts, William J.; Carman, Julie; Poss, Michael A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 21(2017)
Page Start:
4908
Record Type:
Journal Article
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2. Discovery of highly potent, selective, covalent inhibitors of JAK3. Issue 20 (15th October 2017)

Authors:
Kempson, James; Ovalle, Damaso; Guo, Junqing; Wrobleski, Stephen T.; Lin, Shuqun; Spergel, Steven H.; Duan, James J.-W.; Jiang, Bin; Lu, Zhonghui; Das, Jagabandhu; Yang, Bingwei V.; Hynes, John; Wu, Hong; Tokarski, John; Sack, John S.; Khan, Javed; Schieven, Gary; Blatt, Yuval; Chaudhry, Charu; S...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 20(2017)
Page Start:
4622
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

3. Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). Issue 10 (15th May 2016)

Authors:
Guo, Junqing; Watterson, Scott H.; Spergel, Steven H.; Kempson, James; Langevine, Charles M.; Shen, Ding Ren; Yarde, Melissa; Cvijic, Mary Ellen; Banas, Dana; Liu, Richard; Suchard, Suzanne J.; Gillooly, Kathleen; Taylor, Tracy; Rex-Rabe, Sandra; Shuster, David J.; McIntyre, Kim W.; Cornelius, Ge...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 10(2016)
Page Start:
2470
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗