1. Concomitant administration of sGC stimulators with common classes of anti-hypertensive agents results in increased efficacy in spontaneously hypertensive rats. Issue 1 (December 2015) Authors: Germano, Peter; Tobin, Jenny; Jefferson, Robert; Shea, Courtney; Smith, Adaline; Jamie Im, G-Yoon; Sheppeck, James; Wakefield, James; Sykes, Kristie; Ribadeneira, Maria; Rivers, Samuel; Masferrer, Jaime Journal: BMC pharmacology & toxicology Issue: Volume 16:Issue 1(2015) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of IWP-051, a Novel Orally Bioavailable Soluble Guanylate Cyclase Stimulator with Sustained and Dose-Dependent Hemodynamic Effects. Issue 1 (December 2015) Authors: Nakai, Takashi; Perl, Nicholas; Iyengar, Rajesh; Mermerian, Ara; Im, G-Yoon; Lee, Thomas; Rennie, Glen; Jia, James; Renhowe, Paul; Barden, Timothy; Sheppeck, James; Iyer, Karthik; Jung, Joon; Milne, G; Segal, Chrissie; Long, Kimberly; Miyashiro, Joy; Bernier, Sylvie; Jacobson, Sarah; Tobin, Jenny Journal: BMC pharmacology & toxicology Issue: Volume 16:Issue 1(2015) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. IWP-121: a novel sGC stimulator that reduces blood pressure and exhibits anti-fibrotic and anti-inflammatory activities in the Dahl Salt-Sensitive rat model. Issue 1 (December 2015) Authors: Shea, Courtney; Ranganath, Sheila; Liu, Guang; Wachtel, Derek; Germano, Peter; Tobin, Jenny; Zhang, Ping; Rivers, Samuel; Im, G-Yoon; Sheppeck, James; Masferrer, Jaime Journal: BMC pharmacology & toxicology Issue: Volume 16:Issue 1(2015) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗