1. A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [14C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [13C6]-labeled basimglurant in humans. (1st February 2017) Authors: Guerini, Elena; Schadt, Simone; Greig, Gerard; Haas, Ruth; Husser, Christophe; Zell, Manfred; Funk, Christoph; Hartung, Thomas; Gloge, Andreas; Mallalieu, Navita L. Journal: Xenobiotica Issue: Volume 47:Number 2(2017) Page Start: 144 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Absolute Bioavailability of Vemurafenib in Patients With BRAFV600 Mutation–Positive Malignancies. Issue 4 (21st February 2020) Authors: Zhang, Weijiang; Colburn, Dawn; Simmons, Brian; Papai, Zsuzsanna; Bertran, Enric; Schadt, Simone; Husser, Christophe; Forbes, Harper; Roethlisberger, Dieter; Hartung, Thomas Journal: Clinical pharmacology in drug development Issue: Volume 9:Issue 4(2020) Page Start: 496 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Advanced MALDI mass spectrometry imaging in pharmaceutical research and drug development. (February 2019) Authors: Schulz, Sandra; Becker, Michael; Groseclose, M. Reid; Schadt, Simone; Hopf, Carsten Journal: Current opinion in biotechnology Issue: Volume 55(2019) Page Start: 51 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Application of Imaging Techniques to Cases of Drug-Induced Crystal Nephropathy in Preclinical Studies. (27th February 2017) Authors: Lenz, Barbara; Brink, Andreas; Siam, Monira; De Paepe, Anne; Bassett, Simon; Eichinger-Chapelon, Anne; Maliver, Pierre; Neff, Rachel; Niederhauser, Urs; Steinhuber, Bernd; Zurbach, Raphael; Singer, Thomas; Funk, Christoph; Schuler, Franz; Albassam, Mudher; Schadt, Simone Journal: Toxicological sciences Issue: Volume 163:Number 2(2018) Page Start: 409 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator. (27th May 2020) Authors: Nudischer, Ramona; Renggli, Kasper; Bertinetti-Lapatki, Cristina; Hoflack, Jean-Christophe; Flint, Nicholas; Sewing, Sabine; Pedersen, Lykke; Schadt, Simone; Higgins, Larry G; Vardy, Audrey; Lenz, Barbara; Gand, Laurent; Boess, Franziska; Elcombe, Barbara M; Hierlemann, Andreas; Roth, Adrian B Journal: Toxicological sciences Issue: Volume 176:Number 2(2020) Page Start: 329 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Minimizing the risk of chemically reactive metabolite formation of new drug candidates: implications for preclinical drug design. Issue 5 (May 2017) Authors: Brink, Andreas; Pähler, Axel; Funk, Christoph; Schuler, Franz; Schadt, Simone Journal: Drug discovery today Issue: Volume 22:Issue 5(2017) Page Start: 751 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats. (August 2021) Authors: Romero-Palomo, Fernando; Festag, Matthias; Lenz, Barbara; Schadt, Simone; Brink, Andreas; Kipar, Anja; Steinhuber, Bernd; Husser, Christophe; Koller, Erich; Sewing, Sabine; Tessier, Yann; Dzygiel, Pawel; Fischer, Guy; Winter, Michael; Hetzel, Udo; Mihatsch, Michael J.; Braendli-Baiocco, Annamaria Journal: Toxicologic pathology Issue: Volume 49:Number 6(2021) Page Start: 1174 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Shedding light on minipig drug metabolism – elevated amide hydrolysis in vitro. (2nd June 2016) Authors: Jones, Russell; Marschmann, Michaela; Keller, Michael; Qiu, Na Hong; Fowler, Stephen; Singer, Thomas; Schuler, Franz; Funk, Christoph; Schadt, Simone Journal: Xenobiotica Issue: Volume 46:Number 6(2016:Jun.) Page Start: 483 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗