1. Development of a Hybrid Physiologically Based Pharmacokinetic Model with Drug‐Specific Scaling Factors in Rat to Improve Prediction of Human Pharmacokinetics. Issue 11 (9th September 2013) Authors: Sayama, Hiroyuki; Komura, Hiroshi; Kogayu, Motohiro; Iwaki, Masahiro Journal: Journal of pharmaceutical sciences Issue: Volume 102:Issue 11(2013:Nov.) Page Start: 4193 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Quantitative Systems Pharmacology Approaches for Immuno‐Oncology: Adding Virtual Patients to the Development Paradigm. Issue 3 (14th August 2020) Authors: Chelliah, Vijayalakshmi; Lazarou, Georgia; Bhatnagar, Sumit; Gibbs, John P.; Nijsen, Marjoleen; Ray, Avijit; Stoll, Brian; Thompson, R. Adam; Gulati, Abhishek; Soukharev, Serguei; Yamada, Akihiro; Weddell, Jared; Sayama, Hiroyuki; Oishi, Masayo; Wittemer‐Rump, Sabine; Patel, Chirag; Niederalt, Ch... Journal: Clinical pharmacology & therapeutics Issue: Volume 109:Issue 3(2021) Page Start: 605 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non‐small cell lung cancer. (26th June 2021) Authors: Sayama, Hiroyuki; Marcantonio, Diana; Nagashima, Takeyuki; Shimazaki, Masashi; Minematsu, Tsuyoshi; Apgar, Joshua F; Burke, John M.; Wille, Lucia; Nagasaka, Yasuhisa; Kirouac, Daniel C. Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 10:Number 8(2021) Page Start: 864 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗