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Author/Creator Sambrone, Amy

1. Discovery of GNE-502 as an orally bioavailable and potent degrader for estrogen receptor positive breast cancer. (15th October 2021)

Authors:
Zbieg, Jason R.; Liang, Jun; Li, Jun; Blake, Robert A.; Chang, Jae; Friedman, Lori; Goodacre, Simon; Hartman, Steven J.; Rei Ingalla, Ellen; Kiefer, James R.; Kleinheinz, Tracy; Labadie, Sharada; Lai, Tommy; Liao, Jiangpeng; McLean, Nev; Metcalfe, Ciara; Mody, Vidhi; Nannini, Michelle; Ortwine, D...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 50(2021)
Page Start:
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

2. Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model. Issue 18 (15th September 2017)

Authors:
Liang, Jun; Van Abbema, Anne; Balazs, Mercedesz; Barrett, Kathy; Berezhkovsky, Leo; Blair, Wade S.; Chang, Christine; Delarosa, Donnie; DeVoss, Jason; Driscoll, Jim; Eigenbrot, Charles; Goodacre, Simon; Ghilardi, Nico; MacLeod, Calum; Johnson, Adam; Bir Kohli, Pawan; Lai, Yingjie; Lin, Zhonghua; ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 18(2017)
Page Start:
4370
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

5. Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Issue 7 (1st April 2019)

Authors:
Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven; Ingalla, Ellen Rei; Kleinheinz, Tracy; Mody, Vidhi; Nannini, Michelle; Ortwine, Daniel F.; Ran, Yingqing; Sambrone, Amy; Sampath, Deepak; Vinogradova, Maia; Zhong, Yu; Nwachukwu, Jerome C.; Nettles, Kendall W.; Lai...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 7(2019)
Page Start:
905
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗