1. Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties. Issue 18 (15th September 2016) Authors: René, Olivier; Fauber, Benjamin P.; Barnard, Adrian; Chapman, Kerry; Deng, Yuzhong; Eidenschenk, Céline; Everett, Christine; Gobbi, Alberto; Johnson, Adam R.; La, Hank; Norman, Maxine; Salmon, Gary; Summerhill, Susan; Wong, Harvey Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 18(2016) Page Start: 4455 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling. Issue 12 (15th June 2019) Authors: Zak, Mark; Hanan, Emily J.; Lupardus, Patrick; Brown, David G.; Robinson, Colin; Siu, Michael; Lyssikatos, Joseph P.; Romero, F. Anthony; Zhao, Guiling; Kellar, Terry; Mendonca, Rohan; Ray, Nicholas C.; Goodacre, Simon C.; Crackett, Peter H.; McLean, Neville; Hurley, Christopher A.; Yuen, Po-wai;... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 29:Issue 12(2019) Page Start: 1522 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Discovery of imidazo[1, 5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Issue 15 (1st August 2015) Authors: Fauber, Benjamin P.; Gobbi, Alberto; Robarge, Kirk; Zhou, Aihe; Barnard, Adrian; Cao, Jianhua; Deng, Yuzhong; Eidenschenk, Céline; Everett, Christine; Ganguli, Arunima; Hawkins, Julie; Johnson, Adam R.; La, Hank; Norman, Maxine; Salmon, Gary; Summerhill, Susan; Ouyang, Wenjun; Tang, Wei; Wong, Ha... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 15(2015) Page Start: 2907 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties. Issue 18 (15th September 2016) Authors: René, Olivier; Fauber, Benjamin P.; Barnard, Adrian; Chapman, Kerry; Deng, Yuzhong; Eidenschenk, Céline; Everett, Christine; Gobbi, Alberto; Johnson, Adam R.; La, Hank; Norman, Maxine; Salmon, Gary; Summerhill, Susan; Wong, Harvey Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 18(2016) Page Start: 4455 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Discovery of imidazo[1, 5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Issue 15 (1st August 2015) Authors: Fauber, Benjamin P.; Gobbi, Alberto; Robarge, Kirk; Zhou, Aihe; Barnard, Adrian; Cao, Jianhua; Deng, Yuzhong; Eidenschenk, Céline; Everett, Christine; Ganguli, Arunima; Hawkins, Julie; Johnson, Adam R.; La, Hank; Norman, Maxine; Salmon, Gary; Summerhill, Susan; Ouyang, Wenjun; Tang, Wei; Wong, Ha... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 15(2015) Page Start: 2907 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗