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You searched for: Author/Creator Pottie, Ian R.- Pottie, Ian R. [remove] 4
- Biochemistry -- Periodicals 2
- 572 1
- 572.7 1
- 615.19 1
- 616.831 1
- ACE2 Angiotensin-converting enzyme 2 -- ADMET Absorption, distribution, metabolism, excretion, toxicity -- clogD Calculated distribution coefficient -- clogP Calculated partition coefficient -- F(20%) Oral bioavailability score to achieve 20% systemic concentration -- ΔGcalc Gibbs free energy, calculated -- H-bonds Hydrogen bonds -- HBD Hydrogen bond donors -- IC50 Half maximal inhibitory concentration -- Ki Inhibition constant -- LD50 acute oral toxicity median lethal dose -- logPapp Calculated Caco-2 permeability -- logS Calculated aqueous solubility -- MPO Multi-parametric optimization -- Mpro Main protease -- PDB Protein databank -- pKa Acid dissociation constant -- PLpro Papain-like protease -- QM quantum mechanics -- R gas constant -- RdRp RNA-dependent RNA polymerase -- RMSD root mean square deviation -- SARS-CoV Severe acute respiratory syndrome coronavirus -- SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 -- T Absolute temperature -- TPSA Total polar surface area 1
- Alzheimer's disease -- Butyrylcholinesterase -- Acetylcholinesterase -- Single‐photon emission computed tomography -- Molecular imaging -- Neuroimaging -- 123Iodine -- Alzheimer mouse model with 5 familial mutations 1
- Alzheimer's disease -- Periodicals 1
- Alzheimer's disease -- Treatment -- Periodicals 1
- Aβ β-amyloid -- AD Alzheimer's disease -- AChE acetylcholinesterase -- BuChE butyrylcholinesterase -- BuLi butyl lithium -- DTNB 5, 5′-dithiobis 2-nitrobenzoic acid -- HPLC high performance liquid chromatography -- HRMS high resolution mass spectrum -- LRMS low resolution mass spectrum -- NFTs neurofibrillary tangles -- PET Positron Emission Tomography -- TMTFA m-(N, N, N-trimethylammonium)trifluoroacetophenone 1