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Author/Creator Polson, Andrew G.

1. Design, synthesis, and biological evaluation of pyrrolobenzodiazepine-containing hypoxia-activated prodrugs. Issue 23 (1st December 2017)

Authors:
Dragovich, Peter S.; Broccatelli, Fabio; Chen, Jinhua; Fan, Peter; Le, Hoa; Mao, Weiguang; Pillow, Thomas H.; Polson, Andrew G.; Wai, John; Xu, Zijin; Yao, Hui; Zhang, Donglu
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 23(2017)
Page Start:
5300
Record Type:
Journal Article
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3. Evaluation and use of an anti‐cynomolgus monkey CD79b surrogate antibody–drug conjugate to enable clinical development of polatuzumab vedotin. (24th August 2019)

Authors:
Li, Dongwei; Lee, Donna; Dere, Randall C.; Zheng, Bing; Yu, Shang‐Fan; Fuh, Franklin K.; Kozak, Katherine R.; Chung, Shan; Bumbaca Yadav, Daniela; Nazzal, Denise; Danilenko, Dimitry; Go, Mary Ann T.; Williams, Marna; Polson, Andrew G.; Poon, Kirsten Achilles; Prabhu, Saileta
Journal:
British journal of pharmacology
Issue:
Volume 176:Number 19(2019)
Page Start:
3805
Record Type:
Journal Article
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4. Intra-tissue catabolite characterization is a missing link in discovery of ADCs. Issue 1 (January 2019)

Authors:
Zhang, Donglu; Ma, Yong; Yu, Shang-Fan; Pillow, Thomas H.; Sadowsky, Jack D.; Su, Dian; Polson, Andrew G.; Dragovich, Peter S.; Hop, Cornelis ECA.; Khojasteh, S. Cyrus
Journal:
Drug metabolism and pharmacokinetics
Issue:
Volume 34:Issue 1(2019)Supplement
Page Start:
S9
Record Type:
Journal Article
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5. Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response. Issue 1 (1st January 2021)

Authors:
Dela Cruz Chuh, Josefa; Go, MaryAnn; Chen, Yvonne; Guo, Jun; Rafidi, Hanine; Mandikian, Danielle; Sun, Yonglian; Lin, Zhonghua; Schneider, Kellen; Zhang, Pamela; Vij, Rajesh; Sharpnack, Danielle; Chan, Pamela; de la Cruz, Cecile; Sadowsky, Jack; Seshasayee, Dhaya; Koerber, James T.; Pillow, Thoma...
Journal:
MAbs
Issue:
Volume 13:Issue 1(2021)
Page Start:
Record Type:
Journal Article
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6. Preclinical pharmacokinetics and pharmacodynamics of DCLL9718A: An antibody-drug conjugate for the treatment of acute myeloid leukemia. Issue 8 (17th November 2018)

Authors:
Leipold, Douglas D.; Figueroa, Isabel; Masih, Shabkhaiz; Latifi, Brandon; Yip, Victor; Shen, Ben-Quan; Dere, Randall C.; Carrasco-Triguero, Montserrat; Lee, M. Violet; Saad, Ola M.; Liu, Luna; He, Jintang; Su, Dian; Xu, Keyang; Vuillemenot, Brian R.; Laing, Steven T.; Schutten, Melissa; Kozak, Ka...
Journal:
MAbs
Issue:
Volume 10:Issue 8(2018)
Page Start:
1312
Record Type:
Journal Article
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7. Prediction of non-linear pharmacokinetics in humans of an antibody-drug conjugate (ADC) when evaluation of higher doses in animals is limited by tolerability: Case study with an anti-CD33 ADC. Issue 5 (4th July 2018)

Authors:
Figueroa, Isabel; Leipold, Doug; Leong, Steve; Zheng, Bing; Triguero-Carrasco, Montserrat; Fourie-O'Donohue, Aimee; Kozak, Katherine R.; Xu, Keyang; Schutten, Melissa; Wang, Hong; Polson, Andrew G.; Kamath, Amrita V.
Journal:
MAbs
Issue:
Volume 10:Issue 5(2018)
Page Start:
738
Record Type:
Journal Article
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8. Targeting MCL‐1 and BCL‐2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non‐Hodgkin lymphoma: Results from preclinical models and a Phase Ib study. Issue 3 (17th January 2023)

Authors:
Lasater, Elisabeth A.; Amin, Dhara N.; Bannerji, Rajat; Mali, Raghuveer Singh; Barrett, Kathy; Rys, Ryan N.; Oeh, Jason; Lin, Eva; Sterne‐Weiler, Tim; Ingalla, Ellen Rei; Go, MaryAnn; Yu, Shang‐Fan; Krem, Maxwell M.; Arthur, Chris; Hahn, Uwe; Johnston, Anna; Karur, Vinit; Khan, Nadia; Marlton, Pa...
Journal:
American journal of hematology
Issue:
Volume 98:Issue 3(2023)
Page Start:
449
Record Type:
Journal Article
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