1. Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII). Issue 3 (1st February 2018) Authors: Koltun, Dmitry O.; Parkhill, Eric Q.; Kalla, Rao; Perry, Thao D.; Elzein, Elfatih; Li, Xiaofen; Simonovich, Scott P.; Ziebenhaus, Christopher; Hansen, Timothy R.; Marchand, Bruno; Hung, WaiLok K.; Lagpacan, Leanna; Hung, Magdeleine; Aoyama, Ron G.; Murray, Bernard P.; Perry, Jason K.; Somoza, Joh... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 28:Issue 3(2018) Page Start: 541 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of triazolopyridine GS-458967, a late sodium current inhibitor (Late INai) of the cardiac NaV 1.5 channel with improved efficacy and potency relative to ranolazine. Issue 13 (1st July 2016) Authors: Koltun, Dmitry O.; Parkhill, Eric Q.; Elzein, Elfatih; Kobayashi, Tetsuya; Notte, Gregory T.; Kalla, Rao; Jiang, Robert H.; Li, Xiaofen; Perry, Thao D.; Avila, Belem; Wang, Wei-Qun; Smith-Maxwell, Catherine; Dhalla, Arvinder K.; Rajamani, Sridharan; Stafford, Brian; Tang, Jennifer; Mollova, Neven... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 13(2016) Page Start: 3202 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazine. Issue 13 (1st July 2016) Authors: Koltun, Dmitry O.; Parkhill, Eric Q.; Elzein, Elfatih; Kobayashi, Tetsuya; Jiang, Robert H.; Li, Xiaofen; Perry, Thao D.; Avila, Belem; Wang, Wei-Qun; Hirakawa, Ryoko; Smith-Maxwell, Catherine; Wu, Lin; Dhalla, Arvinder K.; Rajamani, Sridharan; Mollova, Nevena; Stafford, Brian; Tang, Jennifer; Be... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 13(2016) Page Start: 3207 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗