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Author/Creator Paehler, Axel

1. Bioavailability and pharmacokinetic profile of balovaptan, a selective, brain-penetrant vasopressin 1a receptor antagonist, in healthy volunteers. (3rd August 2021)

Authors:
Derks, Michael; Lennon-Chrimes, Sian; Guenther, Andreas; Squassante, Lisa; Wandel, Christoph; Szczesny, Piotr; Paehler, Axel; Kletzl, Heidemarie
Journal:
Expert opinion on investigational drugs
Issue:
Volume 30:Number 8(2021)
Page Start:
893
Record Type:
Journal Article
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2. Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein. Issue 6 (8th May 2020)

Authors:
Fischer, Holger; Ullah, Mohammed; de la Cruz, Cecile C; Hunsaker, Thomas; Senn, Claudia; Wirz, Thomas; Wagner, Björn; Draganov, Dragomir; Vazvaei, Faye; Donzelli, Massimiliano; Paehler, Axel; Merchant, Mark; Yu, Li
Journal:
Neuro-oncology
Issue:
Volume 22:Issue 6(2020)
Page Start:
819
Record Type:
Journal Article
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3. How Semiphysiological Population Pharmacokinetic Modeling Incorporating Active Hepatic Uptake Supports Phase II Dose Selection of RO7049389, A Novel Anti–Hepatitis B Virus Drug. Issue 4 (10th March 2021)

Authors:
Cosson, Valérie; Feng, Sheng; Jaminion, Felix; Lemenuel‐Diot, Annabelle; Parrott, Neil; Paehler, Axel; Bo, Qingyan; Jin, Yuyan
Journal:
Clinical pharmacology & therapeutics
Issue:
Volume 109:Issue 4(2021)
Page Start:
1081
Record Type:
Journal Article
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5. Translating pharmacology models effectively to predict therapeutic benefit. Issue 6 (June 2022)

Authors:
Dudal, Sherri; Bissantz, Caterina; Caruso, Antonello; David-Pierson, Pascale; Driessen, Wouter; Koller, Erich; Krippendorff, Ben-Fillippo; Lechmann, Martin; Olivares-Morales, Andrés; Paehler, Axel; Rynn, Caroline; Türck, Dietrich; Van De Vyver, Arthur; Wang, Ken; Winther, Lotte
Journal:
Drug discovery today
Issue:
Volume 27:Issue 6(2022)
Page Start:
1604
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗