Search

Author/Creator Pabst, Timothy M.

2. Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation. (4th November 2018)

Authors:
Luo, Haibin; Tie, Liu; Cao, Mingyan; Hunter, Alan K.; Pabst, Timothy M.; Du, Jiali; Field, Raymond; Li, Yuling; Wang, William K.
Journal:
Biotechnology progress
Issue:
Volume 35:Number 1(2019)
Page Start:
n/a
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Development and scale‐up of a commercial fed batch refolding process for an anti‐CD22 two chain immunotoxin. (2nd September 2014)

Authors:
Linke, Thomas; Aspelund, Matthew T.; Thompson, Christopher; Xi, Guoling; Fulton, Andrew; Wendeler, Michaela; Pabst, Timothy M.; Wang, Xiangyang; Wang, William K.; Ram, Kripa; Hunter, Alan K.
Journal:
Biotechnology progress
Issue:
Volume 30:Number 6(2014)
Page Start:
1380
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

4. Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions. Issue 4 (19th May 2019)

Authors:
Du, Qun; Damschroder, Melissa; Pabst, Timothy M.; Hunter, Alan K.; Wang, William K.; Luo, Haibin
Journal:
MAbs
Issue:
Volume 11:Issue 4(2019)
Page Start:
789
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

5. Safety risk management for low molecular weight process‐related impurities in monoclonal antibody therapeutics: Categorization, risk assessment, testing strategy, and process development with leveraging clearance potential. (6th January 2021)

Authors:
Luo, Haibin; Li, Yuling; Robbins, David; Wang, Sheau‐Chiann; Xi, Guoling; Cox, Matthew; Nicholson, Simone M.; Wei, Chenghong; Pabst, Timothy M.; Wang, William K.
Journal:
Biotechnology progress
Issue:
Volume 37:Number 3(2021)
Page Start:
n/a
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗