Search

Author/Creator Orton, Alexandra L.

1. Drug metabolite identification using ultrahigh‐performance liquid chromatography–ultraviolet spectroscopy and parallelized scans on a tribrid Orbitrap mass spectrometer. (9th March 2020)

Authors:
Wilkinson, Stephen D.; Martin, Scott; Orton, Alexandra L.; Markandu, Roshini; Jones, Barry C.
Journal:
Rapid communications in mass spectrometry
Issue:
Volume 34:Number 10(2020)
Page Start:
n/a
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

2. Improving metabolic stability and removing aldehyde oxidase liability in a 5-azaquinazoline series of IRAK4 inhibitors. Issue 23 (1st December 2020)

Authors:
Degorce, Sébastien L.; Aagaard, Anna; Anjum, Rana; Cumming, Iain A.; Diène, Coura R.; Fallan, Charlene; Johnson, Tony; Leuchowius, Karl-Johan; Orton, Alexandra L.; Pearson, Stuart; Robb, Graeme R.; Rosen, Alan; Scarfe, Graeme B.; Scott, James S.; Smith, James M.; Steward, Oliver R.; Terstiege, In...
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 28:Issue 23(2020)
Page Start:
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Methanol adducts leading to the identification of a reactive aldehyde metabolite of CPAQOP in human liver microsomes by ultra‐high‐performance liquid chromatography/mass spectrometry. (28th November 2016)

Authors:
Martin, Scott; Lenz, Eva M.; Smith, Robin; Temesi, David G.; Orton, Alexandra L.; Clench, Malcolm R.
Journal:
Rapid communications in mass spectrometry
Issue:
Volume 31:Number 1(2017)
Page Start:
145
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗