1. Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins. Issue 11 (29th April 2019) Authors: Migawa, Michael T; Shen, Wen; Wan, W Brad; Vasquez, Guillermo; Oestergaard, Michael E; Low, Audrey; De Hoyos, Cheryl L; Gupta, Ruchi; Murray, Susan; Tanowitz, Michael; Bell, Melanie; Nichols, Joshua G; Gaus, Hans; Liang, Xue-hai; Swayze, Eric E; Crooke, Stanley T; Seth, Punit P Journal: Nucleic acids research Issue: Volume 47:Issue 11(2019) Page Start: 5465 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗