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Author/Creator O'Brien, Julie A.

1. Discovery of 4-arylquinoline-2-carboxamides, highly potent and selective class of mGluR2 negative allosteric modulators: From HTS to activity in animal models. Issue 9 (1st May 2020)

Authors:
Shu, Youheng; Diamond, Tracy L.; Hershey, James C.; Huang, Shaei; Magliaro, Brian C.; O'Brien, Julie A.; Schlegel, Kelly-Ann S.; Puri, Vanita; Uebele, Victor N.; Uslaner, Jason M.; Wang, Cheng; Converso, Antonella
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 9(2020)
Page Start:
Record Type:
Journal Article
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2. Discovery of 5-aryl-1, 3-dihydro-2H-imidazo[4, 5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. Issue 4 (15th February 2016)

Authors:
Layton, Mark E.; Reif, Alexander J.; Hartingh, Timothy J.; Rodzinak, Kevin; Dudkin, Vadim; Wang, Cheng; Arrington, Ken; Kelly, Michael J.; Garbaccio, Robert M.; O'Brien, Julie A.; Magliaro, Brian C.; Uslaner, Jason M.; Huszar, Sarah L.; Fillgrove, Kerry L.; Tang, Cuyue; Kuo, Yuhsin; Jacobson, Mar...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 4(2016)
Page Start:
1260
Record Type:
Journal Article
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3. Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development properties. Issue 12 (15th June 2015)

Authors:
Kuduk, Scott D.; Skudlarek, Jason W.; DiMarco, Christina N.; Bruno, Joseph G.; Pausch, Mark H.; O'Brien, Julie A.; Cabalu, Tamara D.; Stevens, Joanne; Brunner, Joseph; Tannenbaum, Pamela L.; Garson, Susan L.; Savitz, Alan T.; Harrell, Charles M.; Gotter, Anthony L.; Winrow, Christopher J.; Renger...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 12(2015)
Page Start:
2488
Record Type:
Journal Article
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4. Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonists. Issue 6 (15th March 2017)

Authors:
Skudlarek, Jason W.; DiMarco, Christina N.; Babaoglu, Kerim; Roecker, Anthony J.; Bruno, Joseph G.; Pausch, Mark A.; O'Brien, Julie A.; Cabalu, Tamara D.; Stevens, Joanne; Brunner, Joseph; Tannenbaum, Pamela L.; Wuelfing, W. Peter; Garson, Susan L.; Fox, Steven V.; Savitz, Alan T.; Harrell, Charl...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 6(2017)
Page Start:
1364
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗