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Author/Creator Niessen, Karin V.

1. A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment. (15th January 2023)

Authors:
Kaiser, Jesko; Gertzen, Christoph G.W.; Bernauer, Tamara; Höfner, Georg; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Wanner, Klaus T.; Worek, Franz; Thiermann, Horst; Gohlke, Holger
Journal:
Toxicology letters
Issue:
Volume 373(2023)
Page Start:
160
Record Type:
Journal Article
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2. Counteracting desensitization of human α7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning. (1st September 2018)

Authors:
Scheffel, Corinna; Niessen, Karin V.; Rappenglück, Sebastian; Wanner, Klaus T.; Thiermann, Horst; Worek, Franz; Seeger, Thomas
Journal:
Toxicology letters
Issue:
Volume 293(2018)
Page Start:
149
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

4. Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity—An in vitro structure-activity analysis. (1st September 2018)

Authors:
Scheffel, Corinna; Niessen, Karin V.; Rappenglück, Sebastian; Wanner, Klaus. T.; Thiermann, Horst; Worek, Franz; Seeger, Thomas
Journal:
Toxicology letters
Issue:
Volume 293(2018)
Page Start:
157
Record Type:
Journal Article
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6. Synthesis of a Series of Non‐Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor. (27th November 2018)

Authors:
Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst; Wanner, Klaus T.
Journal:
ChemMedChem
Issue:
Volume 13:Number 24(2018)
Page Start:
2653
Record Type:
Journal Article
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7. Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor. (1st August 2018)

Authors:
Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst; Wanner, Klaus T.
Journal:
ChemMedChem
Issue:
Volume 13:Number 17(2018)
Page Start:
1806
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗