1. Application of a systems pharmacology model for translational prediction of hERG‐mediated QTc prolongation. Issue 6 (17th November 2016) Authors: Gotta, Verena; Yu, Zhiyi; Cools, Frank; van Ammel, Karel; Gallacher, David J.; Visser, Sandra A. G.; Sannajust, Frederick; Morissette, Pierre; Danhof, Meindert; van der Graaf, Piet H. Journal: Pharmacology research & perspectives Issue: Volume 4:Issue 6(2016:Dec.) Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Assessment of the clinical cardiac drug‐drug interaction associated with the combination of hepatitis C virus nucleotide inhibitors and amiodarone in guinea pigs and rhesus monkeys. Issue 5 (23rd August 2016) Authors: Regan, Christopher P.; Morissette, Pierre; Regan, Hillary K.; Travis, Jeffery J.; Gerenser, Pamela; Wen, Jianzhong; Fitzgerald, Kevin; Gruver, Shaun; DeGeorge, Joseph J.; Sannajust, Frederick J. Journal: Hepatology Issue: Volume 64:Issue 5(2016:Nov.) Page Start: 1430 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias. (4th September 2019) Authors: Passini, Elisa; Trovato, Cristian; Morissette, Pierre; Sannajust, Frederick; Bueno‐Orovio, Alfonso; Rodriguez, Blanca Journal: British journal of pharmacology Issue: Volume 176:Number 19(2019) Page Start: 3819 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy. Issue 1 (10th November 2019) Authors: Li, Zhihua; Mirams, Gary R.; Yoshinaga, Takashi; Ridder, Bradley J.; Han, Xiaomei; Chen, Janell E.; Stockbridge, Norman L.; Wisialowski, Todd A.; Damiano, Bruce; Severi, Stefano; Morissette, Pierre; Kowey, Peter R.; Holbrook, Mark; Smith, Godfrey; Rasmusson, Randall L.; Liu, Michael; Song, Zhen; ... Journal: Clinical pharmacology & therapeutics Issue: Volume 107:Issue 1(2020) Page Start: 102 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Guiding Chemically Synthesized Peptide Drug Lead Optimization by Derisking Mast Cell Degranulation-Related Toxicities of a NaV1.7 Peptide Inhibitor. (22nd November 2021) Authors: Morissette, Pierre; Li, Nianyu; Ballard, Jeanine E; Vavrek, Marissa; Adams, Gregory L; Regan, Chris; Regan, Hillary; Lee, K J; Wang, Weixun; Burton, Aimee; Chen, Feifei; Gerenser, Pamela; Li, Yuxing; Kraus, Richard L; Tellers, David; Palani, Anand; Zhu, Yuping; Sun, Chengzao; Bianchi, Elisabetta;... Journal: Toxicological sciences Issue: Volume 185:Number 2(2022) Page Start: 170 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores. Issue 11 (1st June 2017) Authors: Dong, Shuzhi; VanGelder, Kelsey; Shi, Zhi-Cai; Yu, Yang; Wu, Zhicai; Ferguson, Ron; Guo, Zack Zhiqiang; Tang, Haifeng; Frie, Jessica; Fu, Qinghong; Gu, Xin; Priest, Birgit T.; Thomas-Fowlkes, Brande; Weinglass, Adam; Margulis, Michael; Liu, Jessica; Pai, Lee-Yuh; Hampton, Caryn; Haimbach, Robin E... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 27:Issue 11(2017) Page Start: 2559 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists. Issue 6 (15th March 2016) Authors: He, Shuwen; Dobbelaar, Peter H.; Guo, Liangqin; Ye, Zhixiong; Liu, Jian; Jian, Tianying; Truong, Quang; Shah, Shrenik K.; Du, Wu; Qi, Hongbo; Bakshi, Raman K.; Hong, Qingmei; Dellureficio, James D.; Sherer, Edward; Pasternak, Alexander; Feng, Zhe; Reibarkh, Mikhail; Lin, Melissa; Samuel, Koppara;... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 6(2016) Page Start: 1529 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗