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Author/Creator Metobo, Sammy

1. Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties. Issue 8 (15th April 2017)

Authors:
Kirschberg, Thorsten A.; Metobo, Sammy; Clarke, Michael O.; Aktoudianakis, Vangelis; Babusis, Darius; Barauskas, Ona; Birkus, Gabriel; Butler, Thomas; Byun, Daniel; Chin, Gregory; Doerffler, Edward; Edwards, Thomas E.; Fenaux, Martijn; Lee, Rick; Lew, Willard; Mish, Michael R.; Murakami, Eisuke; ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 8(2017)
Page Start:
1840
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

2. Structure-guided discovery of a novel, potent, and orally bioavailable 3, 5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor. Issue 3 (1st February 2019)

Authors:
Sperandio, David; Aktoudianakis, Vangelis; Babaoglu, Kerim; Chen, Xiaowu; Elbel, Kristyna; Chin, Gregory; Corkey, Britton; Du, Jinfa; Jiang, Bob; Kobayashi, Tetsuya; Mackman, Richard; Martinez, Ruben; Yang, Hai; Zablocki, Jeff; Kusam, Saritha; Jordan, Kim; Webb, Heather; Bates, Jamie G.; Lad, Lat...
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 27:Issue 3(2019)
Page Start:
457
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗