1. A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy. Issue 5 (24th March 2017) Authors: Daryaee, Fereidoon; Zhang, Zhuo; Gogarty, Kayla R.; Li, Yong; Merino, Jonathan; Fisher, Stewart L.; Tonge, Peter J. Journal: Chemical science Issue: Volume 8:Issue 5(2017) Page Start: 3434 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗