Search

Author/Creator May, Patrick C.

1. Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints. Issue 1 (1st January 2020)

Authors:
Winneroski, Leonard L.; Erickson, Jon A.; Green, Steven J.; Lopez, Jose E.; Stout, Stephanie L.; Porter, Warren J.; Timm, David E.; Audia, James E.; Barberis, Mario; Beck, James P.; Boggs, Leonard N.; Borders, Anthony R.; Boyer, Robert D.; Brier, Richard A.; Hembre, Erik J.; Hendle, Jörg; Garcia-...
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 28:Issue 1(2020)
Page Start:
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

2. P4‐401: Combination Therapy with a Plaque‐Specific Abeta Antibody And A Bace Inhibitor Results in Dramatic Plaque Reduction in a Dose‐Dependent Manner in Aged Pdapp Transgenic Mice. (1st July 2016)

Authors:
Hole, Justin T.; Racke, Margaret M.; Tzaferis, John A.; Liu, Feng; Oluoch, Herold; Ahmed, Zeshan; Fisher, Alice; Anderson, Wesley; Iversent, Philip; Gonzales, Celedon; Yang, Zhixiang; Boggs, Leonard N.; Monk, Scott A.; Mergott, Dustin J.; Yang, Ying YT.; Lu, Jirong; Irizarry, Michael C.; Sims, Jo...
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Supplement 7S(2014)Part 24
Page Start:
P1191
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. P1‐080: Nonclinical Pharmacological Characterization of the Bace1 Inhibitor LY3202626. (1st July 2016)

Authors:
McKinzie, David L.; May, Patrick C.; Boggs, Leonard N.; Yang, Zhixiang; Brier, Richard A.; Monk, Scott A.; Willis, Brian A.; Borders, Anthony R.; Winneroski, Leonard L.; Green, Steven J.; Mergott, Dustin J.
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Supplement 7S(2016)Part 9
Page Start:
P432
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

4. P3‐035: A Correlational Analysis of Exposure and Pharmacodynamic Effects of the Bace1 Inhibitor LY3202626 in PDAPP Mice Following Acute Oral Dosing. (1st July 2016)

Authors:
Boggs, Leonard N.; May, Patrick C.; Yang, Zhixiang; Brier, Richard A.; Monk, Scott A.; Borders, Anthony R.; Winneroski, Leonard L.; Green, Steven J.; Mergott, Dustin J.; McKinzie, David L.
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Supplement 7S(2016)Part 17
Page Start:
P831
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

5. P1‐365: A COMPARISON OF IN VIVO POTENCY IN TWO BACE INHIBITORS AS DETERMINED IN HUMANS AND DOGS. (1st July 2014)

Authors:
Willis, Brian A.; May, Patrick C.; Monk, Scott A.; Lowe, Stephen L.; Friedrich, Stuart; Mergott, Dustin J.; Boggs, Leonard; Gevorkyan, Hakop; Jhee, Stan; Dean, Robert A.; Nakano, Masako; Gonzales, Celedon R.
Journal:
Alzheimer's & dementia
Issue:
Volume 10:Supplement 4S(2014)Part 11
Page Start:
P448
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

6. O4‐04‐02: Investigation of dose‐responses and longitudinal effects of combination therapy with a plaque‐specific amyloid beta antibody and bace inhibitor in aged transgenic mice. (1st July 2015)

Authors:
DeMattos, Ronald B.; Racke, Margaret M.; Hole, Justin T.; Tzaferis, John A.; Liu, Feng; Ahmed, Zeshan; Fisher, Alice; Day, Theresa A.; Anderson, Wesley; Iversent, Philip; Gonzales, Celedon; Yang, Zhixiang; Boggs, Leonard; Monk, Scott A.; Mergott, Dustin J.; Yang, Ying Y.T.; Lu, Jirong; Irizarry, ...
Journal:
Alzheimer's & dementia
Issue:
Volume 11(2015)Supplement 7S:Part 6
Page Start:
P275
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

7. Preparation and biological evaluation of conformationally constrained BACE1 inhibitors. Issue 13 (1st July 2015)

Authors:
Winneroski, Leonard L.; Schiffler, Matthew A.; Erickson, Jon A.; May, Patrick C.; Monk, Scott A.; Timm, David E.; Audia, James E.; Beck, James P.; Boggs, Leonard N.; Borders, Anthony R.; Boyer, Robert D.; Brier, Richard A.; Hudziak, Kevin J.; Klimkowski, Valentine J.; Garcia Losada, Pablo; Mathes...
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 23:Issue 13(2015)
Page Start:
3260
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗