1. Annulation reaction enables the identification of an exocyclic amide tricyclic chemotype as retinoic acid Receptor-Related orphan receptor gamma (RORγ/RORc) inverse agonists. Issue 19 (1st October 2020) Authors: Marcoux, David; Bertrand, Myra Beaudoin; Weigelt, Carolyn A.; Yip, Shiuhang; Galella, Michael; Park, Hyunsoo; Wu, Dauh-Rurng; Wang, Jinhong; Yarde, Melissa; Cvijic, Mary Ellen; Li, Sha; Hynes, John; Tino, Joseph A.; Zhao, Qihong; Dhar, T.G. Murali Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 19(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Identification of highly potent and selective PI3Kδ inhibitors. Issue 13 (1st July 2017) Authors: Marcoux, David; Qin, Lan-Ying; Ruan, Zheming; Shi, Qing; Ruan, Qian; Weigelt, Carolyn; Qiu, Hongchen; Schieven, Gary; Hynes, John; Bhide, Rajeev; Poss, Michael; Tino, Joseph Journal: Bioorganic & medicinal chemistry letters Issue: Volume 27:Issue 13(2017) Page Start: 2849 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Identification of potent tricyclic prodrug S1P1 receptor modulators12. Issue 4 (1st December 2016) Authors: Marcoux, David; Xiao, Hai-Yun; Murali Dhar, T. G.; Xie, Jenny; Lehman-McKeeman, Lois D.; Wu, Dauh-Rurng; Dabros, Marta; Yang, Xiaoxia; Taylor, Tracy L.; Zhou, Xia D.; Heimrich, Elizabeth M.; Thomas, Rochelle; McIntyre, Kim W.; Shi, Hong; Levesque, Paul C.; Sun, Huadong; Yang, Zheng; Marino, Antho... Journal: MedChemComm Issue: Volume 8:Issue 4(2017) Page Start: 725 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Tricyclic sulfones as potent, selective and efficacious RORγt inverse agonists – Exploring C6 and C8 SAR using late-stage functionalization. Issue 23 (1st December 2020) Authors: Shi, Qing; Xiao, Zili; Yang, Michael G.; Marcoux, David; Cherney, Robert J.; Yip, Shiuhang; Li, Peng; Wu, Dauh-Rurng; Weigelt, Carolyn A.; Sack, John; Khan, Javed; Ruzanov, Max; Wang, Jinhong; Yarde, Melissa; Ellen Cvijic, Mary; Li, Sha; Shuster, David J.; Xie, Jenny; Sherry, Tara; Obermeier, Mary Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 23(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗