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- Biomaterials [remove]4
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- HSC Hepatic Stellate Cell -- Hep HepaRG -- 3D three-dimensional -- Hep/HSC Hep and HSC co-culture -- hepatic organoid PDGFR-β -- Platelet derived growth factor receptor β CYP -- cytochrome P450 RIF -- Rifampicin BNF -- β-Naphtoflavone PB -- Phenobarbital MRP2 -- Multidrug resistance-associated protein 2 CMFDA -- 5-chloromethylfluorescein diacetate 2D -- two-dimensional mRNA -- messenger Ribonucleic Acid dCT -- deltaCT gene expression relative to house-keeping gene -- TGFβ Transforming Growth Factor β -- LPS Lipopolysaccharide -- APAP Acetaminophen -- ATP Adenosine Triphosphate -- αSMA alpha Smooth Muscle Actin -- HDAC Histone deacetylase -- CK Cytokine mixture -- VPA Valproic Acid -- CCl4 Carbon Tetrachloride -- EC50 Half Maximal Effective Concentration -- OCR Oxygen consumption rate -- ECAR Extracellular acidification -- Oligo Oligomycin -- FCCP Trifluoromethoxy carbonylcyanide phenylhydrazone -- A + R Antimycin A and Rotenone -- MTX Methotrexate -- ALT Alanine Aminotransferase -- AOP Adverse Outcome Pathway -- DILI Drug-induced liver injury 2
- Organoid -- Liver fibrosis -- DILI -- In vitro -- Hepatic stellate cell -- Hepatocyte -- HepaRG -- APAP -- Methotrexate -- Allyl alcohol 2
- Liver fibrosis -- Hepatic stellate cells -- Hepatocytes -- Liver sinusoidal endothelial cells -- Kupffer cells -- NAFLD -- NASH -- Liver spheroids -- Drug screening 1
- Liver fibrosis -- Stellate cells -- Hepatocytes -- Acetaminophen -- Bioreactor -- Liver spheroids 1