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Author/Creator Lord, Brian

1. Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia. (December 2018)

Authors:
Bhattacharya, Anindya; Lord, Brian; Grigoleit, Jan-Sebastian; He, Yingbo; Fraser, Ian; Campbell, Shannon; Taylor, Natalie; Aluisio, Leah; O'Connor, Jason; Papp, Mariusz; Chrovian, Christa; Carruthers, Nicholas; Lovenberg, Timothy; Letavic, Michael
Journal:
Neuropsychopharmacology
Issue:
Volume 43:Number 13(2018)
Page Start:
2586
Record Type:
Journal Article
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2. Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia. (December 2018)

Authors:
Bhattacharya, Anindya; Lord, Brian; Grigoleit, Jan-Sebastian; He, Yingbo; Fraser, Ian; Campbell, Shannon; Taylor, Natalie; Aluisio, Leah; O'Connor, Jason; Papp, Mariusz; Chrovian, Christa; Carruthers, Nicholas; Lovenberg, Timothy; Letavic, Michael
Journal:
Neuropsychopharmacology
Issue:
Volume 43:Number 13(2018)
Page Start:
2586
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ‐47965567. (17th September 2013)

Authors:
Bhattacharya, Anindya; Wang, Qi; Ao, Hong; Shoblock, James R; Lord, Brian; Aluisio, Leah; Fraser, Ian; Nepomuceno, Diane; Neff, Robert A; Welty, Natalie; Lovenberg, Timothy W; Bonaventure, Pascal; Wickenden, Alan D; Letavic, Michael A
Journal:
British journal of pharmacology
Issue:
Volume 170:Number 3(2013:Oct.)
Page Start:
624
Record Type:
Journal Article
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4. Discovery and SAR studies of 2-alkyl-3-phenyl-2, 4, 5, 6, 7, 8-hexahydropyrazolo[3, 4-d]azepines as 5-HT7/2 inhibitors leading to the identification of a clinical candidate. (1st January 2021)

Authors:
Dvorak, Curt A.; Rudolph, Dale A.; Nepomuceno, Diane; Dvorak, Lisa; Lord, Brian; Fraser, Ian; Bonaventure, Pascal; Lovenberg, Timothy; Carruthers, Nicholas I.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 31(2021)
Page Start:
Record Type:
Journal Article
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5. Preclinical characterization of substituted 6, 7-dihydro-[1, 2, 4]triazolo[4, 3-a]pyrazin-8(5H)-one P2X7 receptor antagonists. Issue 2 (15th January 2016)

Authors:
Ameriks, Michael K.; Ao, Hong; Carruthers, Nicholas I.; Lord, Brian; Ravula, Suchitra; Rech, Jason C.; Savall, Brad M.; Wall, Jessica L.; Wang, Qi; Bhattacharya, Anindya; Letavic, Michael A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 2(2016)
Page Start:
257
Record Type:
Journal Article
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6. P2X7 receptor antagonism reduces the severity of spontaneous seizures in a chronic model of temporal lobe epilepsy. (June 2016)

Authors:
Amhaoul, Halima; Ali, Idrish; Mola, Marco; Van Eetveldt, Annemie; Szewczyk, Krystyna; Missault, Stephan; Bielen, Kenny; Kumar-Singh, Samir; Rech, Jason; Lord, Brian; Ceusters, Marc; Bhattacharya, Anindya; Dedeurwaerdere, Stefanie
Journal:
Neuropharmacology
Issue:
Volume 105(2016)
Page Start:
175
Record Type:
Journal Article
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7. P2X7 receptor antagonism reduces the severity of spontaneous seizures in a chronic model of temporal lobe epilepsy. (June 2016)

Authors:
Amhaoul, Halima; Ali, Idrish; Mola, Marco; Van Eetveldt, Annemie; Szewczyk, Krystyna; Missault, Stephan; Bielen, Kenny; Kumar-Singh, Samir; Rech, Jason; Lord, Brian; Ceusters, Marc; Bhattacharya, Anindya; Dedeurwaerdere, Stefanie
Journal:
Neuropharmacology
Issue:
Volume 105(2016)
Page Start:
175
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

8. Novel methyl substituted 1-(5, 6-dihydro-[1, 2, 4]triazolo[4, 3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists. Issue 16 (15th August 2015)

Authors:
Rudolph, Dale A.; Alcazar, Jesus; Ameriks, Michael K.; Anton, Ana Belen; Ao, Hong; Bonaventure, Pascal; Carruthers, Nicholas I.; Chrovian, Christa C.; De Angelis, Meri; Lord, Brian; Rech, Jason C.; Wang, Qi; Bhattacharya, Anindya; Andres, Jose Ignacio; Letavic, Michael A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 16(2015)
Page Start:
3157
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

9. Novel methyl substituted 1-(5, 6-dihydro-[1, 2, 4]triazolo[4, 3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists. Issue 16 (15th August 2015)

Authors:
Rudolph, Dale A.; Alcazar, Jesus; Ameriks, Michael K.; Anton, Ana Belen; Ao, Hong; Bonaventure, Pascal; Carruthers, Nicholas I.; Chrovian, Christa C.; De Angelis, Meri; Lord, Brian; Rech, Jason C.; Wang, Qi; Bhattacharya, Anindya; Andres, Jose Ignacio; Letavic, Michael A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 16(2015)
Page Start:
3157
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗