Search

Author/Creator Lawson, J. David

3. Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1. Issue 12 (15th June 2016)

Authors:
Cheruvallath, Zacharia; Tang, Mingnam; McBride, Christopher; Komandla, Mallareddy; Miura, Joanne; Ton-Nu, Thu; Erikson, Phil; Feng, Jun; Farrell, Pamela; Lawson, J. David; Vanderpool, Darin; Wu, Yiqin; Dougan, Douglas R.; Plonowski, Artur; Holub, Corine; Larson, Chris
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 12(2016)
Page Start:
2774
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

4. Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 2. Issue 12 (15th June 2016)

Authors:
McBride, Christopher; Cheruvallath, Zacharia; Komandla, Mallareddy; Tang, Mingnam; Farrell, Pamela; Lawson, J. David; Vanderpool, Darin; Wu, Yiqin; Dougan, Douglas R.; Plonowski, Artur; Holub, Corine; Larson, Chris
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 12(2016)
Page Start:
2779
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

5. Fragment optimization and elaboration strategies – the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Issue 12 (27th September 2022)

Authors:
Smith, Christopher R.; Kulyk, Svitlana; Ahmad, Misbha Ud Din; Arkhipova, Valentina; Christensen, James G.; Gunn, Robin J.; Ivetac, Anthony; Ketcham, John M.; Kuehler, Jon; Lawson, J. David; Thomas, Nicole C.; Wang, Xiaolun; Marx, Matthew A.
Journal:
RSC medicinal chemistry
Issue:
Volume 13:Issue 12(2022)
Page Start:
1549
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

6. Fragment-based drug discovery of potent and selective MKK3/6 inhibitors. Issue 3 (1st February 2016)

Authors:
Adams, Mark; Kobayashi, Toshitake; Lawson, J. David; Saitoh, Morihisa; Shimokawa, Kenichiro; Bigi, Simone V.; Hixon, Mark S.; Smith, Christopher R.; Tatamiya, Takayuki; Goto, Masayuki; Russo, Joseph; Grimshaw, Charles E.; Swann, Steven
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 3(2016)
Page Start:
1086
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

7. Fragment-based drug discovery of potent and selective MKK3/6 inhibitors. Issue 3 (1st February 2016)

Authors:
Adams, Mark; Kobayashi, Toshitake; Lawson, J. David; Saitoh, Morihisa; Shimokawa, Kenichiro; Bigi, Simone V.; Hixon, Mark S.; Smith, Christopher R.; Tatamiya, Takayuki; Goto, Masayuki; Russo, Joseph; Grimshaw, Charles E.; Swann, Steven
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 3(2016)
Page Start:
1086
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

8. Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate. Issue 4 (15th February 2017)

Authors:
Keung, Walter; Boloor, Amogh; Brown, Jason; Kiryanov, Andre; Gangloff, Anthony; Lawson, J. David; Skene, Robert; Hoffman, Isaac; Atienza, Josephine; Kahana, Jason; De Jong, Ron; Farrell, Pamela; Balakrishna, Deepika; Halkowycz, Petro
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 4(2017)
Page Start:
1099
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗