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Author/Creator Lamb, Michelle L.

1. Discovery of 2, 6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinases. Issue 8 (1st May 2018)

Authors:
Gingipalli, Lakshmaiah; Block, Michael H.; Bao, Larry; Cooke, Emma; Dakin, Les A.; Denz, Christopher R.; Ferguson, Andrew D.; Johannes, Jeffrey W.; Larsen, Nicholas A.; Lyne, Paul D.; Pontz, Timothy W.; Wang, Tao; Wu, Xiaoyun; Wu, Allan; Zhang, Hai-Jun; Zheng, Xiaolan; Dowling, James E.; Lamb, Mi...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 8(2018)
Page Start:
1336
Record Type:
Journal Article
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2. Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering. Issue 24 (15th December 2015)

Authors:
Johannes, Jeffrey W.; Almeida, Lynsie; Daly, Kevin; Ferguson, Andrew D.; Grosskurth, Shaun E.; Guan, Huiping; Howard, Tina; Ioannidis, Stephanos; Kazmirski, Steven; Lamb, Michelle L.; Larsen, Nicholas A.; Lyne, Paul D.; Mikule, Keith; Ogoe, Claude; Peng, Bo; Petteruti, Philip; Read, Jon A.; Su, N...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 24(2015)
Page Start:
5743
Record Type:
Journal Article
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3. Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clustering. Issue 19 (1st October 2016)

Authors:
Gu, Chungang; Lamb, Michelle L.; Johannes, Jeffrey W.; Sylvester, Mark A.; Eisman, Mark S.; Harrison, Rane A.; Hu, Haiqing; Kazmirski, Steven; Mikule, Keith; Peng, Bo; Su, Nancy; Wang, Wenxian; Ye, Qing; Zheng, Xiaolan; Lyne, Paul D.; Scott, David A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 19(2016)
Page Start:
4775
Record Type:
Journal Article
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4. Structure‐Based Design of Selective Noncovalent CDK12 Inhibitors. (26th January 2018)

Authors:
Johannes, Jeffrey W.; Denz, Christopher R.; Su, Nancy; Wu, Allan; Impastato, Anna C.; Mlynarski, Scott; Varnes, Jeffrey G.; Prince, D. Bryan; Cidado, Justin; Gao, Ning; Haddrick, Malcolm; Jones, Natalie H.; Li, Shaobin; Li, Xiuwei; Liu, Yang; Nguyen, Toan B.; O'Connell, Nichole; Rivers, Emma; Rob...
Journal:
ChemMedChem
Issue:
Volume 13:Number 3(2018)
Page Start:
231
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗