1. A Novel In Vivo‐Active Small Molecule Inducer of Progranulin for the Treatment of Frontotemporal Dementia. (20th December 2022) Authors: Blain, Jean‐François; Chen, Angela Y.P.; Brand, Morgan A.; Lanter, James C.; Holler, Christopher J.; Brendel, Jerusha K.; Koenig, Gerhard; Burnett, Duane A.; Hurst, Raymond S. Journal: Alzheimer's & dementia Issue: Volume 18(2022)Supplement 10 Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer's disease. Issue 1 (December 2016) Authors: Blain, Jean-François; Bursavich, Matthew; Freeman, Emily; Hrdlicka, Lori; Hodgdon, Hilliary; Chen, Ting; Costa, Don; Harrison, Bryce; Kapadnis, Sudarshan; Murphy, Deirdre; Nolan, Scott; Tu, Zhiming; Tang, Cuyue; Burnett, Duane; Patzke, Holger; Koenig, Gerhard Journal: Alzheimer's research & therapy Issue: Volume 8:Issue 1(2016) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Continuous infusion of the α7 nicotinic acetylcholine receptor agonist EVP-6124 produces no signs of tolerance at memory-enhancing doses in rats. Issue 4 (June 2015) Authors: van Goethem, Nick P.; Prickaerts, Jos; Welty, Devin; Flood, Dorothy G.; Koenig, Gerhard Journal: Behavioural pharmacology Issue: Volume 26:Issue 4(2015) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Continuous infusion of the α7 nicotinic acetylcholine receptor agonist EVP-6124 produces no signs of tolerance at memory-enhancing doses in rats: a pharmacokinetic and behavioral study. Issue 4 (June 2015) Authors: van Goethem, Nick P.; Prickaerts, Jos; Welty, Devin; Flood, Dorothy G.; Koenig, Gerhard Journal: Behavioural pharmacology Issue: Volume 26:Issue 4(2015) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Discovery of oxazoline enhancers of cellular progranulin release. (15th January 2023) Authors: Peng, Xiaowen; Lanter, James C.; Y.-P. Chen, Angela; Brand, Morgan A.; Wozniak, Mary K.; Hoekman, Steven; Longin, Ondřej; Regeling, Hendrik; Zonneveld, Wim; P. L. Bell, Roel; Koenig, Gerhard; Hurst, Raymond S.; Blain, Jean-François; Burnett, Duane A. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 80(2023) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Discovery of quinuclidine modulators of cellular progranulin. (1st September 2021) Authors: Lanter, James C.; Chen, Angela Y.-P.; Williamson, Toni; Koenig, Gerhard; Blain, Jean-François; Burnett, Duane A. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 47(2021) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Effects of a novel phosphodiesterase 10A inhibitor in non-human primates: A therapeutic approach for schizophrenia with improved side effect profile. (November 2016) Authors: Masilamoni, Gunasingh J.; Uthayathas, Subramanian; Koenig, Gerhard; Leventhal, Liza; Papa, Stella M. Journal: Neuropharmacology Issue: Volume 110(2016) Part A Page Start: 449 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. O4‐02‐01: PHASE 2A RANDOMIZED, DOUBLE‐BLIND, PLACEBO‐CONTROLLED TRIAL OF THE HISTONE DEACETYLASE INHIBITOR (HDACI), FRM‐0334, IN ASYMPTOMATIC CARRIERS OF, OR PATIENTS WITH FRONTOTEMPORAL LOBAR DEGENERATION (FTLD) DUE TO, PROGRANULIN GENE MUTATIONS. (1st July 2019) Authors: Boxer, Adam L.; Moebius, Hans; Harris, Baruch; Boeve, Bradley F.; Borroni, Barbara; van Swieten, John C.; Grossman, Murray; Pasquier, Florence; Frisoni, Giovanni B.; Mummery, Catherine J.; Vandenberghe, Rik; Le Ber, Isabelle; Hannequin, Didier; McGinnis, Scott M.; Auriacombe, Sophie; Onofrj, Marc... Journal: Alzheimer's & dementia Issue: Volume 15:Supplement 7S(2019)Part 23 Page Start: P1231 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. S1‐02‐03: NACHR7 AGONIST FOR ALZHEIMER'S DISEASE. (1st July 2014) Authors: Koenig, Gerhard Journal: Alzheimer's & dementia Issue: Volume 10:Supplement 4S(2014)Part 1 Page Start: P123 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗