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Author/Creator Kinzel, Olaf

1. Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach. Issue 12 (15th June 2020)

Authors:
Steeneck, Christoph; Gege, Christian; Kinzel, Olaf; Albers, Michael; Kleymann, Gerald; Schlüter, Thomas; Schulz, Andreas; Xue, Xiaohua; Cummings, Maxwell D.; Fourie, Anne M.; Leonard, Kristi A.; Scott, Brian; Edwards, James P.; Hoffmann, Thomas; Goldberg, Steven D.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 12(2020)
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Record Type:
Journal Article
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2. Discovery and optimization of substituted oxalamides as novel heme-displacing IDO1 inhibitors. (1st February 2021)

Authors:
Steeneck, Christoph; Kinzel, Olaf; Anderhub, Simon; Hornberger, Martin; Pinto, Sheena; Morschhaeuser, Barbara; Albers, Michael; Sonnek, Christina; Czekańska, Marta; Hoffmann, Thomas
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 33(2021)
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Record Type:
Journal Article
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3. Discovery of highly potent heme-displacing IDO1 inhibitors based on a spirofused bicyclic scaffold. (1st February 2021)

Authors:
Kinzel, Olaf; Steeneck, Christoph; Anderhub, Simon; Hornberger, Martin; Pinto, Sheena; Morschhaeuser, Barbara; Albers, Michael; Sonnek, Christina; Wang, Yansong; Mallinger, Aurélie; Czekańska, Marta; Hoffmann, Thomas
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 33(2021)
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Record Type:
Journal Article
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4. Identification and biological evaluation of thiazole-based inverse agonists of RORγt. Issue 9 (15th May 2018)

Authors:
Gege, Christian; Cummings, Maxwell D.; Albers, Michael; Kinzel, Olaf; Kleymann, Gerald; Schlüter, Thomas; Steeneck, Christoph; Nelen, Marina I.; Milligan, Cindy; Spurlino, John; Xue, Xiaohua; Leonard, Kristi; Edwards, James P.; Fourie, Anne; Goldberg, Steven D.; Hoffmann, Thomas
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 9(2018)
Page Start:
1446
Record Type:
Journal Article
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5. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Issue 15 (1st August 2016)

Authors:
Kinzel, Olaf; Steeneck, Christoph; Schlüter, Thomas; Schulz, Andreas; Gege, Christian; Hahn, Ulrike; Hambruch, Eva; Hornberger, Martin; Spalwisz, Adriana; Frick, Katharina; Perović-Ottstadt, Sanja; Deuschle, Ulrich; Burnet, Michael; Kremoser, Claus
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 15(2016)
Page Start:
3746
Record Type:
Journal Article
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6. Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt. Issue 12 (15th June 2020)

Authors:
Gege, Christian; Albers, Michael; Kinzel, Olaf; Kleymann, Gerald; Schlüter, Thomas; Steeneck, Christoph; Hoffmann, Thomas; Xue, Xiaohua; Cummings, Maxwell D.; Spurlino, John; Milligan, Cynthia; Fourie, Anne M.; Edwards, James P.; Leonard, Kristi; Coe, Kevin; Scott, Brian; Pippel, Dan; Goldberg, S...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 12(2020)
Page Start:
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

7. The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine‐rich glycoprotein. Issue 11 (13th November 2014)

Authors:
Deuschle, Ulrich; Birkel, Manfred; Hambruch, Eva; Hornberger, Martin; Kinzel, Olaf; Perović‐Ottstadt, Sanja; Schulz, Andreas; Hahn, Ulrike; Burnet, Michael; Kremoser, Claus
Journal:
International journal of cancer
Issue:
Volume 136:Issue 11(2015:Jun. 01)
Page Start:
2693
Record Type:
Journal Article
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