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Author/Creator Kinberger, Garth A.

1. A convenient synthesis of 5′-triantennary N-acetyl-galactosamine clusters based on nitromethanetrispropionic acid. Issue 9 (1st May 2016)

Authors:
Migawa, Michael T.; Prakash, Thazha P.; Vasquez, Guillermo; Wan, W. Brad; Yu, Jinghua; Kinberger, Garth A.; Østergaard, Michael E.; Swayze, Eric E.; Seth, Punit P.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 9(2016)
Page Start:
2194
Record Type:
Journal Article
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2. Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes. Issue 21 (23rd October 2017)

Authors:
Tanowitz, Michael; Hettrick, Lisa; Revenko, Alexey; Kinberger, Garth A.; Prakash, Thazha P.; Seth, Punit P.
Journal:
Nucleic acids research
Issue:
Volume 45:Issue 21(2017)
Page Start:
12388
Record Type:
Journal Article
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3. Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes. Issue 15 (1st August 2016)

Authors:
Kinberger, Garth A.; Prakash, Thazha P.; Yu, Jinghua; Vasquez, Guillermo; Low, Audrey; Chappell, Alfred; Schmidt, Karsten; Murray, Heather M.; Gaus, Hans; Swayze, Eric E.; Seth, Punit P.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 15(2016)
Page Start:
3690
Record Type:
Journal Article
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4. Evaluation of the effect of 2′-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice. Issue 23 (15th December 2018)

Authors:
Prakash, Thazha P.; Yu, Jinghua; Kinberger, Garth A.; Low, Audrey; Jackson, Michaela; Rigo, Frank; Swayze, Eric E.; Seth, Punit P.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 23/24(2018)
Page Start:
3774
Record Type:
Journal Article
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5. Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity. Issue 11 (1st May 2017)

Authors:
Prakash, Thazha P.; Lima, Walt F.; Murray, Heather M.; Li, Wenyu; Kinberger, Garth A.; Chappell, Alfred E.; Gaus, Hans; Seth, Punit P.; Bhat, Balkrishen; Crooke, Stanley T.; Swayze, Eric E.
Journal:
Nucleic acids research
Issue:
Volume 45:Issue 11(2017)
Page Start:
6994
Record Type:
Journal Article
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6. Solid-phase synthesis of 5′-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistry. Issue 19 (1st October 2015)

Authors:
Prakash, Thazha P.; Brad Wan, W.; Low, Audrey; Yu, Jinghua; Chappell, Alfred E.; Gaus, Hans; Kinberger, Garth A.; Østergaard, Michael E.; Migawa, Michael T.; Swayze, Eric E.; Seth, Punit P.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 19(2015)
Page Start:
4127
Record Type:
Journal Article
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7. Solid-phase synthesis of 5′-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistry. Issue 19 (1st October 2015)

Authors:
Prakash, Thazha P.; Brad Wan, W.; Low, Audrey; Yu, Jinghua; Chappell, Alfred E.; Gaus, Hans; Kinberger, Garth A.; Østergaard, Michael E.; Migawa, Michael T.; Swayze, Eric E.; Seth, Punit P.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 19(2015)
Page Start:
4127
Record Type:
Journal Article
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8. Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA. Issue 12 (15th June 2016)

Authors:
Prakash, Thazha P.; Kinberger, Garth A.; Murray, Heather M.; Chappell, Alfred; Riney, Stan; Graham, Mark J.; Lima, Walt F.; Swayze, Eric E.; Seth, Punit P.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 12(2016)
Page Start:
2817
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗