1. 552 SUMOylation inhibitor TAK-981 activates NK cells and macrophages via Type I interferon signaling and shows synergistic activity in combination with rituximab and daratumumab in preclinical models. (10th December 2020) Authors: Nakamura, Akito; Song, Keli; Grossman, Stephen; Xega, Kristina; Zhang, Yuhong; Berger, Allison; Berger, Allison; Shapiro, Gary; Huszar, Dennis Journal: Journal for immunotherapy of cancer Issue: Volume 8(2020)Supplement 3 Page Start: A334 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Identification of azabenzimidazoles as potent JAK1 selective inhibitors. Issue 1 (1st January 2016) Authors: Vasbinder, Melissa M.; Alimzhanov, Marat; Augustin, Martin; Bebernitz, Geraldine; Bell, Kirsten; Chuaqui, Claudio; Deegan, Tracy; Ferguson, Andrew D.; Goodwin, Kelly; Huszar, Dennis; Kawatkar, Aarti; Kawatkar, Sameer; Read, Jon; Shi, Jie; Steinbacher, Stefan; Steuber, Holger; Su, Qibin; Toader, D... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 1(2016) Page Start: 60 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Next-generation sequencing identifies a novel ELAVL1–TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208. Issue 12 (1st December 2016) Authors: Tron, Adriana E.; Keeton, Erika K.; Ye, Minwei; Casas-Selves, Matias; Chen, Huawei; Dillman, Keith S.; Gale, Rosemary E.; Stengel, Chloe; Zinda, Michael; Linch, David C.; Lai, Zhongwu; Khwaja, Asim; Huszar, Dennis Journal: Leukemia & lymphoma Issue: Volume 57:Issue 12(2016:Dec.) Page Start: 2927 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. PIM and AKT kinase inhibitors show synergistic cytotoxicity in acute myeloid leukaemia that is associated with convergence on mTOR and MCL1 pathways. (30th June 2014) Authors: Meja, Koremu; Stengel, Chloe; Sellar, Rob; Huszar, Dennis; Davies, Barry R.; Gale, Rosemary E.; Linch, David C.; Khwaja, Asim Journal: British journal of haematology Issue: Volume 167:Number 1(2014:Oct.) Page Start: 69 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗