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Author/Creator Huang, Xiangping

1. Cover Feature: Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies (ChemMedChem 5/2019). (5th March 2019)

Authors:
Ghosh, Arun K.; Brindisi, Margherita; Yen, Yu‐Chen; Lendy, Emma K.; Kovela, Satish; Cárdenas, Emilio Leal; Reddy, Bhavanam Sekhara; Rao, Kalapala Venketeswara; Downs, Deborah; Huang, Xiangping; Tang, Jordan; Mesecar, Andrew D.
Journal:
ChemMedChem
Issue:
Volume 14:Number 5(2019)
Page Start:
513
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

2. Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes. Issue 5 (4th February 2016)

Authors:
Ghosh, Arun K.; Reddy, Bhavanam Sekhara; Yen, Yu-Chen; Cárdenas, Emilio L.; Rao, Kalapala Venkateswara; Downs, Deborah; Huang, Xiangping; Tang, Jordan; Mesecar, Andrew D.
Journal:
Chemical science
Issue:
Volume 7:Issue 5(2016:May)
Page Start:
3117
Record Type:
Journal Article
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3. Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1′-P2′ ligands. Issue 11 (1st June 2017)

Authors:
Ghosh, Arun K.; Brindisi, Margherita; Yen, Yu-Chen; Cárdenas, Emilio L.; Ella-Menye, Jean-Rene; Kumaragurubaran, Nagaswamy; Huang, Xiangping; Tang, Jordan; Mesecar, Andrew D.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 11(2017)
Page Start:
2432
Record Type:
Journal Article
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4. Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand. Issue 15 (15th August 2018)

Authors:
Ghosh, Arun K.; Ghosh, Koena; Brindisi, Margherita; Lendy, Emma K.; Yen, Yu-Chen; Kumaragurubaran, Nagaswamy; Huang, Xiangping; Tang, Jordan; Mesecar, Andrew D.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 15(2018)
Page Start:
2605
Record Type:
Journal Article
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5. Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies. (5th February 2019)

Authors:
Ghosh, Arun K.; Brindisi, Margherita; Yen, Yu‐Chen; Lendy, Emma K.; Kovela, Satish; Cárdenas, Emilio Leal; Reddy, Bhavanam Sekhara; Rao, Kalapala Venketeswara; Downs, Deborah; Huang, Xiangping; Tang, Jordan; Mesecar, Andrew D.
Journal:
ChemMedChem
Issue:
Volume 14:Number 5(2019)
Page Start:
545
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

7. Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand. Issue 3 (1st February 2015)

Authors:
Ghosh, Arun K.; Brindisi, Margherita; Yen, Yu-Chen; Xu, Xiaoming; Huang, Xiangping; Devasamudram, Thippeswamy; Bilcer, Geoffrey; Lei, Hui; Koelsch, Gerald; Mesecar, Andrew D.; Tang, Jordan
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 3(2015)
Page Start:
668
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗