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Author/Creator Hol, Wim G. J.

1. A binding hotspot in Trypanosoma cruzi histidyl‐tRNA synthetase revealed by fragment‐based crystallographic cocktail screens. (1st August 2015)

Authors:
Koh, Cho Yeow; Kallur Siddaramaiah, Latha; Ranade, Ranae M.; Nguyen, Jasmine; Jian, Tengyue; Zhang, Zhongsheng; Gillespie, J. Robert; Buckner, Frederick S.; Verlinde, Christophe L. M. J.; Fan, Erkang; Hol, Wim G. J.
Journal:
Acta crystallographica
Issue:
Volume 71:Part 8(2015:Aug.)
Page Start:
1684
Record Type:
Journal Article
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2. Identification of Potent Inhibitors of the Trypanosoma brucei Methionyl-tRNA Synthetase via High-Throughput Orthogonal Screening. (January 2015)

Authors:
Pedró-Rosa, Laura; Buckner, Frederick S.; Ranade, Ranae M.; Eberhart, Christina; Madoux, Franck; Gillespie, J. Robert; Koh, Cho Yeow; Brown, Steven; Lohse, Jacqueline; Verlinde, Christophe L. M.; Fan, Erkang; Bannister, Thomas; Scampavia, Louis; Hol, Wim G. J.; Spicer, Timothy; Hodder, Peter
Journal:
Journal of biomolecular screening
Issue:
Volume 20:Number 1(2015)
Page Start:
122
Record Type:
Journal Article
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4. Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei. Issue 8 (18th May 2020)

Authors:
Zhang, Zhongsheng; Barros-Álvarez, Ximena; Gillespie, J. Robert; Ranade, Ranae M.; Huang, Wenlin; Shibata, Sayaka; Molasky, Nora M. R.; Faghih, Omeed; Mushtaq, Aisha; Choy, Robert K. M.; de Hostos, Eugenio; Hol, Wim G. J.; Verlinde, Christophe L. M. J.; Buckner, Frederick S.; Fan, Erkang
Journal:
RSC medicinal chemistry
Issue:
Volume 11:Issue 8(2020)
Page Start:
885
Record Type:
Journal Article
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5. The crystal structure of the drug target Mycobacterium tuberculosis methionyl‐tRNA synthetase in complex with a catalytic intermediate. Issue 4 (12th April 2018)

Authors:
Barros-Álvarez, Ximena; Turley, Stewart; Ranade, Ranae M.; Gillespie, J. Robert; Duster, Nicole A.; Verlinde, Christophe L. M. J.; Fan, Erkang; Buckner, Frederick S.; Hol, Wim G. J.
Journal:
Acta crystallographica
Issue:
Volume 74:Issue 4(2018:Apr.)
Page Start:
245
Record Type:
Journal Article
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