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You searched for: Author/Creator Hirase, Keizo- Hirase, Keizo [remove] 4
- Bioorganic chemistry -- Periodicals 4
- Pharmaceutical chemistry -- Periodicals 4
- 572 2
- 615.19 2
- Biochemistry -- Periodicals 2
- Chemistry, Clinical -- Periodicals 2
- Chemistry, Organic -- Periodicals 2
- Chimie bio-organique -- Périodiques 2
- Chimie pharmaceutique -- Périodiques 2
- ADME-Tox absorption, distribution, metabolism, excretion, and toxicity -- AUC area under the curve -- BnSH benzyl mercaptan -- Xantphos 4, 5-bis(diphenylphosphino)-9, 9-dimethylxanthene -- CYP2C19 hepatic cytochrome P450 2C19 -- CYP3A4 hepatic cytochrome P450 3A4 -- DBU 1, 8-diazabicyclo[5.4.0]undec-7-ene -- DSC differential scanning calorimetry -- DMB 2, 4-dimethoxybenzyl -- DMAP 4-dimethylaminopyridine -- DMSO dimethyl sulfoxide -- Boc2O di-tert-butyl dicarbonate -- DMPK drug metabolism and pharmacokinetics -- ESI electrospray ionization -- IC50 half-maximal inhibitory concentration -- HPLC high-performance liquid chromatography -- HRMS high-resolution mass spectrometry -- hERG human ether-a-go-go-related gene -- iv intravenous injection -- LC/MS/MS liquid chromatography with tandem mass spectrometry -- LDA lithium diisopropylamide -- mp melting point -- MeO methoxy -- NCS N-chlorosuccinimide -- po er os -- P-CAB potassium-competitive acid blocker -- PPI proton pump inhibitor -- Py pyridyl -- rt room temperature -- THF tetrahydrofuran -- TG-DTA thermogravimetrydifferential thermal analysis -- TLC thin-layer chromatography 1