1. 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration. Issue 5 (16th June 2021) Authors: Wang, Hongbing; Brown, Paul C.; Chow, Edwin C.Y.; Ewart, Lorna; Ferguson, Stephen S.; Fitzpatrick, Suzanne; Freedman, Benjamin S.; Guo, Grace L.; Hedrich, William; Heyward, Scott; Hickman, James; Isoherranen, Nina; Li, Albert P.; Liu, Qi; Mumenthaler, Shannon M.; Polli, James; Proctor, William R.... Journal: Clinical and translational science Issue: Volume 14:Issue 5(2021) Page Start: 1659 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. A10 - Characterization of differential tissue abundance of major non-cyp enzymes in human. (2020) Authors: Neradugomma, Naveen; Basit, Abdul; Takahashi, Ryan; Fan, Peter; Smith, Bill; Murray, Bernard; Heyward, Scott; Wolford, Chris; Kelly, Edward J.; Prasad, Bhagwat Journal: Drug metabolism and pharmacokinetics Issue: Volume 35(2020)Supplement 1 Page Start: S21 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Aldehyde oxidase activity in human vascular tissue and its potential contribution to extra-hepatic metabolism. Issue 1 (January 2019) Authors: Kozminski, Kirk; Heyward, Scott; Zientek, Michael Journal: Drug metabolism and pharmacokinetics Issue: Volume 34:Issue 1(2019)Supplement Page Start: S62 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Can transporter-expressing cells predict rosuvastatin uptake clearance in suspended or plated human hepatocytes?. Issue 1 (January 2019) Authors: Kumar, Vineet; Salphati, Laurent; Hop, Cornelis E.C.A.; Rowbottom, Christopher; Xiao, Guangqing; Lai, Yurong; Mathias, Anita; Chu, Xiaoyan; Humphreys, W. Griffith; Liao, Mingxiang; Chen, Laigao; Tóth, Beáta; Juhasz, Viktoria; Heyward, Scott; Unadkat, Jashvant Journal: Drug metabolism and pharmacokinetics Issue: Volume 34:Issue 1(2019)Supplement Page Start: S22 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Does plasma membrane and total transporter abundance differ between suspended, plated, sandwich culture hepatocytes and human liver tissue?. Issue 1 (January 2019) Authors: Kumar, Vineet; Salphati, Laurent; Hop, Cornelis E.C.A.; Rowbottom, Christopher; Xiao, Guangqing; Lai, Yurong; Mathias, Anita; Chu, Xiaoyan; Humphreys, W.Griffith; Liao, Mingxiang; Chen, Laigao; Heyward, Scott; Unadkat, Jashvant Journal: Drug metabolism and pharmacokinetics Issue: Volume 34:Issue 1(2019)Supplement Page Start: S17 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library. (22nd September 2018) Authors: Lynch, Caitlin; Mackowiak, Bryan; Huang, Ruili; Li, Linhao; Heyward, Scott; Sakamuru, Srilatha; Wang, Hongbing; Xia, Menghang Journal: Toxicological sciences Issue: Volume 167:Number 1(2019) Page Start: 282 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. P129 - In-vivo transporter-mediated hepatic clearance of rosuvastatin in humans could be better predicted using transporter-expressing cells than hepatocytes. (2020) Authors: Kumar, Vineet; Ishida, Kazuya; Salphati, Laurent; Hop, Cornelis E.C. A.; Rowbottom, Christopher; Xiao, Guangqing; Lai, Yurong; Mathias, Anita; Chu, Xiaoyan; Humphreys, W. Griffith; Liao, Mingxiang; Tóth, Beáta; Szilvásy, Nóra; Heyward, Scott; Unadkat, Jashvant D. Journal: Drug metabolism and pharmacokinetics Issue: Volume 35(2020)Supplement 1 Page Start: S61 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. P35 - The use of primary cryopreserved human hepatocytes as a model for non-alcoholic fatty liver disease (NAFLD) related changes in phase I and phase II enzyme activities. (2020) Authors: Cottier, Karissa; Le, Xuan; Heyward, Scott Journal: Drug metabolism and pharmacokinetics Issue: Volume 35(2020)Supplement 1 Page Start: S31 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Prediction of Hepatobiliary Clearances and Hepatic Concentrations of Transported Drugs in Humans Using Rosuvastatin as a Model Drug. Issue 3 (19th March 2022) Authors: Storelli, Flavia; Li, Cindy Yanfei; Sachar, Madhav; Kumar, Vineet; Heyward, Scott; Sáfár, Zsolt; Kis, Emese; Unadkat, Jashvant D. Journal: Clinical pharmacology & therapeutics Issue: Volume 112:Issue 3(2022) Page Start: 593 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗