1. Development of a therapeutic approach for hereditary diseases with prime editing: A study on Alzheimer's disease. (1st February 2022) Authors: Tremblay, Guillaume; Rousseau, Joël; Happi‐Mbakam, Cedric; Guyon, Antoine; Tremblay, Jacques P Journal: Alzheimer's & dementia Issue: Volume 17(2021)Supplement 3 Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Development of a therapeutic approach for hereditary diseases with prime editing: A study on Alzheimer's disease. (December 2021) Authors: Tremblay, Guillaume; Rousseau, Joël; Happi‐Mbakam, Cedric; Guyon, Antoine; Tremblay, Jacques P Journal: Alzheimer's & dementia Issue: Volume 17(2021)Supplement 3 Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Insertion of the Icelandic mutation (A673T) in the APP gene using the CRISPR/Cas9 base editing and Prime editing technologies, a preventive treatment for Alzheimer?. (31st December 2021) Authors: Tremblay, Jacques P.; Tremblay, Guillaume; Guyon, Antoine; Joël, Rousseau; Happi‐Mbakam, Cedric Journal: Alzheimer's & dementia Issue: Volume 17(2021)Supplement 2 Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Insertion of the protective APP A673T mutation by CRISPR/Cas9 base editing or PRIME editing. (17th December 2021) Authors: Tremblay, Jacques P; Guyon, Antoine; Rousseau, Joël; Tremblay, Guillaume; Begin, Francis-Gabriel; Lamothe, Gabriel Journal: Innovation in aging Issue: Volume 5(2021)Supplement 1 Page Start: 669 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Insertion of the protective APP A673T mutation by CRISPR/Cas9 base editing or PRIME editing. (17th December 2021) Authors: Tremblay, Jacques; Guyon, Antoine; Rousseau, Joël; Tremblay, Guillaume; Begin, Francis-Gabriel; Lamothe, Gabriel Journal: Innovation in aging Issue: Volume 5(2021)Supplement 1 Page Start: 665 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Optimization of in vitro gene delivery to neurons containing an APP gene with a mutation responsible for familial Alzheimer's disease for the development of a base editing therapy: Human/Prevention (clinical). (7th December 2020) Authors: Tremblay, Jacques P.; Guyon, Antoine; Joël, Rousseau P. Journal: Alzheimer's & dementia Issue: Volume 16(2020)Supplement 9 Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. P1‐002: BASE EDITING STRATEGY ALLOWS HIGH FREQUENCY INSERTION OF THE PROTECTIVE A673T MUTATION IN THE APP GENE TO PREVENT THE DEVELOPMENT OF ALZHEIMER'S DISEASE. (1st July 2019) Authors: Guyon, Antoine; Rousseau, Joël; Bertin, Tom; Raymond, Frédéric; Tremblay, Jacques P. Journal: Alzheimer's & dementia Issue: Volume 15:Supplement 7(2019)Part 4 Page Start: P228 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗