1. An amide-based sulfenamide prodrug of gamma secretase inhibitor BMS–708163 delivers parent drug from an oral conventional solid dosage form in male beagle dog. Issue 3 (1st February 2020) Authors: Guarino, Victor R.; Olson, Richard E.; Everlof, J. Gerry; Wang, Nenghui; McDonald, Ivar; Haskell, Roy; Clarke, Wendy; Lentz, Kimberley A. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 3(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies. Issue 21 (1st November 2020) Authors: Hu, Zilun; Wang, Cailan; Glunz, Peter W.; Li, Julia; Cheadle, Nathan L.; Chen, Alice Y.; Chen, Xue-Qing; Myers, Joseph E.; Guarino, Victor R.; Rose, Anne; Sack, John S.; Sitkoff, Doree; Taylor, David S.; Xu, Songmei; Yan, Chunhong; Zhang, Hongwei; Zhang, Lisa; Hennan, James; Adam, Leonard P.; Wex... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 21(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗