1. Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRASG12C. (1st April 2020) Authors: Mortier, Jérémie; Friberg, Anders; Badock, Volker; Moosmayer, Dieter; Schroeder, Jens; Steigemann, Patrick; Siegel, Franziska; Gradl, Stefan; Bauser, Marcus; Hillig, Roman C.; Briem, Hans; Eis, Knut; Bader, Benjamin; Nguyen, Duy; Christ, Clara D. Journal: ChemMedChem Issue: Volume 15:Number 10(2020) Page Start: 827 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162. Issue 2 (8th February 2021) Authors: Moosmayer, Dieter; Hilpmann, André; Hoffmann, Jutta; Schnirch, Lennart; Zimmermann, Katja; Badock, Volker; Furst, Laura; Eaton, John K.; Viswanathan, Vasanthi S.; Schreiber, Stuart L.; Gradl, Stefan; Hillig, Roman C. Journal: Acta crystallographica Issue: Volume 77:Issue 2(2021) Page Start: 237 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. DDRE-29. DE NOVO PYRIMIDINE SYNTHESIS IS A TARGETABLE VULNERABILITY IN IDH-MUTANT GLIOMA. (25th March 2021) Authors: Shi, Diana D; Wang, Adam C; Levitt, Michael M; Endress, Jennifer E; Xu, Min; Gao, Wenhua; Khanal, Januka; Bonal, Dennis; Kornblum, Harley I; Nguyen, Quang-De; Gradl, Stefan; Sutter, Andreas; Jeffers, Michael; Janzer, Andreas; Cahill, Daniel P; Ligon, Keith L; Abdullah, Kalil G; Harris, Isaac S; K... Journal: Neuro-oncology advances Issue: Volume 3(2021)Supplement 1 Page Start: i12 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. (September 2021) Authors: Gradl, Stefan; Steuber, Holger; Weiske, Joerg; Szewczyk, Magda M.; Schmees, Norbert; Siegel, Stephan; Stoeckigt, Detlef; Christ, Clara D.; Li, Fengling; Organ, Shawna; Abbey, Megha; Kennedy, Steven; Chau, Irene; Trush, Viacheslav; Barsyte-Lovejoy, Dalia; Brown, Peter J.; Vedadi, Masoud; Arrowsmit... Journal: SLAS discovery Issue: Volume 26:Number 8(2021) Page Start: 947 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Front Cover: Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRASG12C (ChemMedChem 10/2020). (19th May 2020) Authors: Mortier, Jérémie; Friberg, Anders; Badock, Volker; Moosmayer, Dieter; Schroeder, Jens; Steigemann, Patrick; Siegel, Franziska; Gradl, Stefan; Bauser, Marcus; Hillig, Roman C.; Briem, Hans; Eis, Knut; Bader, Benjamin; Nguyen, Duy; Christ, Clara D. Journal: ChemMedChem Issue: Volume 15:Number 10(2020) Page Start: 808 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗