1. Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity. Issue 21 (1st November 2015) Authors: Charnley, Adam K.; Convery, Máire A.; Lakdawala Shah, Ami; Jones, Emma; Hardwicke, Philip; Bridges, Angela; Ouellette, Michael; Totoritis, Rachel; Schwartz, Benjamin; King, Bryan W.; Wisnoski, David D.; Kang, James; Eidam, Patrick M.; Votta, Bartholomew J.; Gough, Peter J.; Marquis, Robert W.; Be... Journal: Bioorganic & medicinal chemistry Issue: Volume 23:Issue 21(2015) Page Start: 7000 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Genetic Inhibition of Receptor Interacting Protein Kinase-1 Reduces Cell Death and Improves Functional Outcome After Intracerebral Hemorrhage in Mice. Issue 9 (September 2017) Authors: Lule, Sevda; Wu, Limin; McAllister, Lauren M.; Edmiston, William J.; Chung, Joon Yong; Levy, Emily; Zheng, Yi; Gough, Peter J.; Bertin, John; Degterev, Alexei; Lo, Eng H.; Whalen, Michael J. Journal: Stroke Issue: Volume 48:Issue 9(2017) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. High throughput screening identifies ATP-competitive inhibitors of the NLRP1 inflammasome. Issue 14 (15th July 2015) Authors: Harris, Philip A.; Duraiswami, Chaya; Fisher, Donald T.; Fornwald, James; Hoffman, Sandra J.; Hofmann, Glenn; Jiang, Ming; Lehr, Ruth; McCormick, Patricia M.; Nickels, Leng; Schwartz, Benjamin; Wu, Zining; Zhang, Guofeng; Marquis, Robert W.; Bertin, John; Gough, Peter J. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 14(2015) Page Start: 2739 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. High throughput screening identifies ATP-competitive inhibitors of the NLRP1 inflammasome. Issue 14 (15th July 2015) Authors: Harris, Philip A.; Duraiswami, Chaya; Fisher, Donald T.; Fornwald, James; Hoffman, Sandra J.; Hofmann, Glenn; Jiang, Ming; Lehr, Ruth; McCormick, Patricia M.; Nickels, Leng; Schwartz, Benjamin; Wu, Zining; Zhang, Guofeng; Marquis, Robert W.; Bertin, John; Gough, Peter J. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 14(2015) Page Start: 2739 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Identification of an antibody‐based immunoassay for measuring direct target binding of RIPK1 inhibitors in cells and tissues. Issue 6 (6th December 2017) Authors: Finger, Joshua N.; Brusq, Jean‐Marie; Campobasso, Nino; Cook, Michael N.; Deutsch, Jennifer; Haag, Heather; Harris, Philip A.; Jenkins, Earl L.; Joglekar, Devika; Lich, John D.; Maguire, Sean; Nagilla, Rakesh; Rivera, Elizabeth J.; Sun, Helen; Votta, Bartholomew J.; Bertin, John; Gough, Peter J. Journal: Pharmacology research & perspectives Issue: Volume 5:Issue 6(2017) Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis. Issue 4 (April 2017) Authors: Zille, Marietta; Karuppagounder, Saravanan S.; Chen, Yingxin; Gough, Peter J.; Bertin, John; Finger, Joshua; Milner, Teresa A.; Jonas, Elizabeth A.; Ratan, Rajiv R. Journal: Stroke Issue: Volume 48:Issue 4(2017) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Randomized clinical study of safety, pharmacokinetics, and pharmacodynamics of RIPK1 inhibitor GSK2982772 in healthy volunteers. Issue 6 (26th October 2017) Authors: Weisel, Kathleen; Scott, Nicola E.; Tompson, Debra J.; Votta, Bartholomew J.; Madhavan, Sujith; Povey, Kat; Wolstenholme, Allen; Simeoni, Monica; Rudo, Todd; Richards‐Peterson, Lauren; Sahota, Tarjinder; Wang, J. Gene; Lich, John; Finger, Joshua; Verticelli, Adeline; Reilly, Michael; Gough, Peter... Journal: Pharmacology research & perspectives Issue: Volume 5:Issue 6(2017) Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗