1. Concomitant administration of sGC stimulators with common classes of anti-hypertensive agents results in increased efficacy in spontaneously hypertensive rats. Issue 1 (December 2015) Authors: Germano, Peter; Tobin, Jenny; Jefferson, Robert; Shea, Courtney; Smith, Adaline; Jamie Im, G-Yoon; Sheppeck, James; Wakefield, James; Sykes, Kristie; Ribadeneira, Maria; Rivers, Samuel; Masferrer, Jaime Journal: BMC pharmacology & toxicology Issue: Volume 16:Issue 1(2015) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator. (15th May 2021) Authors: Rennie, Glen R.; Barden, Timothy C.; Bernier, Sylvie G.; Carvalho, Andrew; Deming, Renee; Germano, Peter; Hudson, Colleen; Im, G-Yoon J.; Iyengar, Rajesh R.; Jia, Lei; Jung, Joon; Kim, Elise; Lee, Thomas W.-H.; Mermerian, Ara; Moore, Joel; Nakai, Takashi; Perl, Nicholas R.; Tobin, Jenny; Zimmer, ... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 40(2021) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Discovery of IWP-051, a Novel Orally Bioavailable Soluble Guanylate Cyclase Stimulator with Sustained and Dose-Dependent Hemodynamic Effects. Issue 1 (December 2015) Authors: Nakai, Takashi; Perl, Nicholas; Iyengar, Rajesh; Mermerian, Ara; Im, G-Yoon; Lee, Thomas; Rennie, Glen; Jia, James; Renhowe, Paul; Barden, Timothy; Sheppeck, James; Iyer, Karthik; Jung, Joon; Milne, G; Segal, Chrissie; Long, Kimberly; Miyashiro, Joy; Bernier, Sylvie; Jacobson, Sarah; Tobin, Jenny Journal: BMC pharmacology & toxicology Issue: Volume 16:Issue 1(2015) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. IWP-121: a novel sGC stimulator that reduces blood pressure and exhibits anti-fibrotic and anti-inflammatory activities in the Dahl Salt-Sensitive rat model. Issue 1 (December 2015) Authors: Shea, Courtney; Ranganath, Sheila; Liu, Guang; Wachtel, Derek; Germano, Peter; Tobin, Jenny; Zhang, Ping; Rivers, Samuel; Im, G-Yoon; Sheppeck, James; Masferrer, Jaime Journal: BMC pharmacology & toxicology Issue: Volume 16:Issue 1(2015) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical‐stage soluble guanylate cyclase stimulator in rats. Issue 2 (20th April 2020) Authors: Banijamali, Ali R.; Carvalho, Andrew E.; Wakefield, James D.; Germano, Peter; Barden, Timothy C.; Tobin, Jenny V.; Zimmer, Daniel P.; Masferrer, Jaime L.; Profy, Albert T.; Currie, Mark G.; Todd Milne, G. Journal: Pharmacology research & perspectives Issue: Volume 8:Issue 2(2020) Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Quantitative mass balance, tissue distribution, pharmacokinetics and biotransformation pathway of praliciguat, a clinical-stage sgc stimulator, after oral administration in rats. Issue 1 (January 2019) Authors: Banijamali, Ali; Carvalho, Andrew; Wakefield, James; Germano, Peter; Ribadeneira, Maria; Barden, Timothy; Zimmer, Daniel; Masferrer, Jaime; Profy, Albert; Currie, Mark; Milne, Todd; Germano, Peter Journal: Drug metabolism and pharmacokinetics Issue: Volume 34:Issue 1(2019)Supplement Page Start: S56 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗