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Author/Creator Garneau, Michel

1. A prodrug strategy for the oral delivery of a poorly soluble HCV NS5B thumb pocket 1 polymerase inhibitor using self-emulsifying drug delivery systems (SEDDS). Issue 2 (15th January 2015)

Authors:
Beaulieu, Pierre L.; De Marte, Josie; Garneau, Michel; Luo, Laibin; Stammers, Timothy; Telang, Chitra; Wernic, Dominik; Kukolj, George; Duan, Jianmin
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 2(2015)
Page Start:
210
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

2. A prodrug strategy for the oral delivery of a poorly soluble HCV NS5B thumb pocket 1 polymerase inhibitor using self-emulsifying drug delivery systems (SEDDS). Issue 2 (15th January 2015)

Authors:
Beaulieu, Pierre L.; De Marte, Josie; Garneau, Michel; Luo, Laibin; Stammers, Timothy; Telang, Chitra; Wernic, Dominik; Kukolj, George; Duan, Jianmin
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 2(2015)
Page Start:
210
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

4. Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 1: Mitigating the genotoxic liability of an aniline metabolite. Issue 5 (1st March 2015)

Authors:
Beaulieu, Pierre L.; Bolger, Gordon; Duplessis, Martin; Gagnon, Alexandre; Garneau, Michel; Stammers, Timothy; Kukolj, George; Duan, Jianmin
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 5(2015)
Page Start:
1135
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

5. Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 1: Mitigating the genotoxic liability of an aniline metabolite. Issue 5 (1st March 2015)

Authors:
Beaulieu, Pierre L.; Bolger, Gordon; Duplessis, Martin; Gagnon, Alexandre; Garneau, Michel; Stammers, Timothy; Kukolj, George; Duan, Jianmin
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 5(2015)
Page Start:
1135
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

6. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Issue 12 (23rd July 2018)

Authors:
Gerlach, Kai; Hobson, Scott; Eickmeier, Christian; Groß, Ulrike; Braun, Clemens; Sieger, Peter; Garneau, Michel; Hoerer, Stefan; Heine, Niklas
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 26:Issue 12(2018)
Page Start:
3227
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

7. Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity. Issue 5 (1st March 2015)

Authors:
Beaulieu, Pierre L.; Bolger, Gordon; Deon, Dan; Duplessis, Martin; Fazal, Gulrez; Gagnon, Alexandre; Garneau, Michel; LaPlante, Steven; Stammers, Timothy; Kukolj, George; Duan, Jianmin
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 5(2015)
Page Start:
1140
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

8. Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity. Issue 5 (1st March 2015)

Authors:
Beaulieu, Pierre L.; Bolger, Gordon; Deon, Dan; Duplessis, Martin; Fazal, Gulrez; Gagnon, Alexandre; Garneau, Michel; LaPlante, Steven; Stammers, Timothy; Kukolj, George; Duan, Jianmin
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 5(2015)
Page Start:
1140
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗