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Author/Creator Fretland, Adrian J.

1. Characterization of 3, 3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors. Issue 19 (1st October 2016)

Authors:
Kuklish, Steven L.; Antonysamy, Stephen; Bhattachar, Shobha N.; Chandrasekhar, Srinivasan; Fisher, Matthew J.; Fretland, Adrian J.; Gooding, Karen; Harvey, Anita; Hughes, Norman E.; Luz, John G.; Manninen, Peter R.; McGee, James E.; Navarro, Antonio; Norman, Bryan H.; Partridge, Katherine M.; Qui...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 19(2016)
Page Start:
4824
Record Type:
Journal Article
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2. Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades. (June 2020)

Authors:
Davies, Michael; Jones, Rhys D.O.; Grime, Ken; Jansson-Löfmark, Rasmus; Fretland, Adrian J.; Winiwarter, Susanne; Morgan, Paul; McGinnity, Dermot F.
Journal:
Trends in pharmacological sciences
Issue:
Volume 41:Number 6(2020)
Page Start:
390
Record Type:
Journal Article
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3. Investigating the effect of autoinduction in cynomolgus monkeys of a novel anticancer MDM2 antagonist, idasanutlin, and relevance to humans. (2nd August 2016)

Authors:
Glenn, Kelli J.; Yu, Li J.; Reddy, Micaela B.; Fretland, Adrian J.; Parrott, Neil; Hussain, Sazzad; Palacios, Mary; Vazvaei, Faye; Zhi, Jianguo; Tuerck, Dietrich
Journal:
Xenobiotica
Issue:
Volume 46:Number 8(2016:Aug.)
Page Start:
667
Record Type:
Journal Article
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4. Multiscale Model Identifies Improved Schedule for Treatment of Acute Myeloid Leukemia In Vitro With the Mcl‐1 Inhibitor AZD5991. (17th September 2020)

Authors:
Goliaei, Ardeshir; Woods, Haley A.; Tron, Adriana E.; Belmonte, Matthew A.; Secrist, J. Paul; Ferguson, Douglas; Drew, Lisa; Fretland, Adrian J.; Aldridge, Bree B.; Gibbons, Francis D.
Journal:
CPT: pharmacometrics & systems pharmacology
Issue:
Volume 9:Number 10(2020)
Page Start:
561
Record Type:
Journal Article
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