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Author/Creator Frech, Matthias

1. Kinetics for Drug Discovery: an industry-driven effort to target drug residence time. Issue 6 (June 2017)

Authors:
Schuetz, Doris A.; de Witte, Wilhelmus Egbertus Arnout; Wong, Yin Cheong; Knasmueller, Bernhard; Richter, Lars; Kokh, Daria B.; Sadiq, S. Kashif; Bosma, Reggie; Nederpelt, Indira; Heitman, Laura H.; Segala, Elena; Amaral, Marta; Guo, Dong; Andres, Dorothee; Georgi, Victoria; Stoddart, Leigh A.; H...
Journal:
Drug discovery today
Issue:
Volume 22:Issue 6(2017)
Page Start:
896
Record Type:
Journal Article
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2. Ligand‐Induced Conformational Changes in HSP90 Monitored Time Resolved and Label Free—Towards a Conformational Activity Screening for Drug Discovery. Issue 31 (3rd July 2018)

Authors:
Güldenhaupt, Jörn; Amaral, Marta; Kötting, Carsten; Schartner, Jonas; Musil, Djordje; Frech, Matthias; Gerwert, Klaus
Journal:
Angewandte Chemie international edition
Issue:
Volume 57:Issue 31(2018)
Page Start:
9955
Record Type:
Journal Article
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3. Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2. Issue 5 (20th May 2021)

Authors:
Berger, Benedict-Tilman; Amaral, Marta; Kokh, Daria B.; Nunes-Alves, Ariane; Musil, Djordje; Heinrich, Timo; Schröder, Martin; Neil, Rebecca; Wang, Jing; Navratilova, Iva; Bomke, Joerg; Elkins, Jonathan M.; Müller, Susanne; Frech, Matthias; Wade, Rebecca C.; Knapp, Stefan
Journal:
Cell chemical biology
Issue:
Volume 28:Issue 5(2021)
Page Start:
686
Record Type:
Journal Article
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4. Zeitaufgelöst und markerfrei gemessene ligandeninduzierte Konformationsänderungen von HSP90 – hin zu einem Konformationsaktivitätsscreening für die Wirkstoffentwicklung. (3rd July 2018)

Authors:
Güldenhaupt, Jörn; Amaral, Marta; Kötting, Carsten; Schartner, Jonas; Musil, Djordje; Frech, Matthias; Gerwert, Klaus
Journal:
Angewandte Chemie
Issue:
Volume 130:Number 31(2018)
Page Start:
10103
Record Type:
Journal Article
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