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You searched for: Author/Creator Fraser, Graeme L.- Fraser, Graeme L. [remove] 5
- Menopause -- Periodicals 3
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- AUCu unbound area-under-the-curve -- (S)-BINAP (S)-(-)-(1, 1′-binaphthalene-2, 2′-diyl)bis(diphenylphosphine) -- CLu unbound systemic clearance rate -- Compd compound -- DIEA N, N-diisopropyl ethylamine, EtOAc, ethyl acetate -- FFA2 receptor free fatty acid-2 receptor -- Fsp3 fraction sp3 = number of sp3 hybridized carbons/total carbon count -- GPCR G-protein coupled receptor -- GTP- γ 35S guanosine 5′-O-[gamma-thio]triphosphate -- KO knock-out mice model -- HATU N-[(Dimethylamino)-1H-1, 2, 3-triazolo-[4, 5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide -- HTS high-throughput screening -- NMM N-methyl morpholine -- OGTT oral glucose tolerance test -- POC proof-of-concept -- PK pharmacokinetics -- SAR structure-activity relationship -- T1/2 elimination half-life 1
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