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You searched for: Author/Creator Fochtman, P.- Fochtman, P. [remove] 7
- Toxicology -- Periodicals 7
- 363.179 4
- 615.9 3
- Toxicity testing -- In vitro -- Periodicals 3
- BAC benzalkonium chloride -- Cat 1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat 2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorized in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CO corneal opacity -- Conj conjunctival redness (CR) and/or conjunctival chemosis (CC) -- CO pers. D21 CO persistence on day 21 -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- CP contact period -- CP1% 60-min CP with a 1% w/v concentration of the chemical -- CP10% 60-min CP with a 10% w/v concentration of the chemical -- CP3.5% 60-min CP with a 3.5% w/v concentration of the chemical -- DRD Draize eye test Reference Database -- FNR false negative rate -- FPR false positive rate -- IR iritis -- MP mucus production -- MP CP1% amount of mucus produced during CP1% -- MP CP10% amount of mucus produced during CP10% -- MP CP3.5% amount of mucus produced during CP3.5% -- NC negative control -- OECD Organization for Economic Co-operation and Development -- PC positive control -- pers persistence -- SMI Slug Mucosal Irritation -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals 1
- BfR Bundesinstitut für Risikobewertung, Federal Institute for risk assessment, Germany -- Cat1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- EU European Union -- EU CLP EU Classification, Labelling and Packaging regulation (EC) No 1272/2008 -- FN false negative -- FP false positive -- JRC European Commission - Joint Research Centre, Varese, Italy -- No Cat chemicals not classified for serious eye damage/eye irritation under GHS/EU CLP -- OECD Organisation for Economic Co-operation and Development -- QSAR quantitative structure-activity relationship -- SAR structure-activity relationship -- REACH registration, evaluation, authorisation and restriction of chemicals -- Regulation (EC) no 1907/2006 -- SMILES simplified molecular input line entry specification -- TN true negative -- TP true positive -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals -- VITO Flemish Institute for Technological Research 1
- CON4EI -- Eye irritation/serious eye damage -- Slug Mucosal Irritation (SMI) test method 1
- CON4EI -- Ocular irritation -- In silico models -- QSAR -- Computational modelling 1
- CON4EI -- Ocular irritation -- Short Time Exposure (STE) assay -- OECD Test Guideline 491 1
- Cat 1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat 2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-catagorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CO Corneal Opacity -- Conj conjunctival redness (CR) and/or conjunctival chemosis (CC) -- CO pers. D21 CO persistence on day 21 -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- DRD Draize eye test Reference Database -- DMSO dimethyl sulfoxide -- FNR false negative rate -- FPR false positive rate -- IR iritis, MTT, 3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide -- OD optical density -- OECD Organization for Economic Co-operation and Development -- PC positive control -- pers persistence -- SC solvent control -- SIRC Statens Seruminstitut Rabbit Cornea -- DPBS Dulbecco's Phosphate Buffered Saline -- SLS sodium lauryl sulfate -- STE Short Time Exposure -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals 1