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You searched for: Author/Creator Fitzek, Martina

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1. A small molecule inhibitor of HER3: a proof-of-concept study. Issue 17 (10th September 2020)

2. Design of selective PI3Kα inhibitors starting from a promiscuous pan kinase scaffold. Issue 13 (1st July 2015)

3. Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1, 3, 4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1, 2, 4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers. Issue 22 (15th November 2015)

4. Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors. Issue 13 (1st July 2017)

5. Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours. Issue 9 (1st May 2017)

6. Discovery of a series of 8-(2, 3-dihydro-1, 4-benzoxazin-4-ylmethyl)-2-morpholino-4-oxo-chromene-6-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours. Issue 9 (1st May 2016)