1. Changing the HTS Paradigm: AI-Driven Iterative Screening for Hit Finding. (February 2021) Authors: Dreiman, Gabriel H. S.; Bictash, Magda; Fish, Paul V.; Griffin, Lewis; Svensson, Fredrik Journal: SLAS discovery Issue: Volume 26:Number 2(2021) Page Start: 257 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen123. Issue 8 (16th May 2019) Authors: Atkinson, Benjamin N.; Steadman, David; Zhao, Yuguang; Sipthorp, James; Vecchia, Luca; Ruza, Reinis R.; Jeganathan, Fiona; Lines, Georgie; Frew, Sarah; Monaghan, Amy; Kjær, Svend; Bictash, Magda; Jones, E. Yvonne; Fish, Paul V. Journal: MedChemComm Issue: Volume 10:Issue 8(2019) Page Start: 1361 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Large-scale synthesis of Notum inhibitor 1-(2, 4-dichloro-3-(trifluoromethyl)-phenyl)-1H-1, 2, 3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step. Issue 41 (16th September 2022) Authors: Atkinson, Benjamin N.; Willis, Nicky J.; Smith, Jennifer; Gill, Rebecca; Ali, Jody; Xu, Zhou; Lai, Ping-Shan; Fish, Paul V. Journal: RSC advances Issue: Volume 12:Issue 41(2022) Page Start: 26497 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. New approaches for the treatment of Alzheimer's disease. Issue 2 (15th January 2019) Authors: Fish, Paul V.; Steadman, David; Bayle, Elliott D.; Whiting, Paul Journal: Bioorganic & medicinal chemistry letters Issue: Volume 29:Issue 2(2019) Page Start: 125 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms. Issue 18 (15th September 2016) Authors: Spurr, Sophie S.; Bayle, Elliott D.; Yu, Wenyu; Li, Fengling; Tempel, Wolfram; Vedadi, Masoud; Schapira, Matthieu; Fish, Paul V. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 18(2016) Page Start: 4518 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms. Issue 18 (15th September 2016) Authors: Spurr, Sophie S.; Bayle, Elliott D.; Yu, Wenyu; Li, Fengling; Tempel, Wolfram; Vedadi, Masoud; Schapira, Matthieu; Fish, Paul V. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 18(2016) Page Start: 4518 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors. (October 2021) Authors: Devkota, Kanchan; Schapira, Matthieu; Perveen, Sumera; Khalili Yazdi, Aliakbar; Li, Fengling; Chau, Irene; Ghiabi, Pegah; Hajian, Taraneh; Loppnau, Peter; Bolotokova, Albina; Satchell, Karla J. F.; Wang, Ke; Li, Deyao; Liu, Jing; Smil, David; Luo, Minkui; Jin, Jian; Fish, Paul V.; Brown, Peter J.... Journal: SLAS discovery Issue: Volume 26:Number 9(2021) Page Start: 1200 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Regioselective and enantiospecific synthesis of the HSP co-inducer arimoclomol from chiral glycidyl derivatives. Issue 46 (21st November 2017) Authors: Atkinson, Benjamin N.; Woodward, Hannah L.; Sipthorp, James; Fish, Paul V. Journal: Organic & biomolecular chemistry Issue: Volume 15:Issue 46(2017) Page Start: 9794 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Scaffold-hopping identifies furano[2, 3-d]pyrimidine amides as potent Notum inhibitors. Issue 3 (1st February 2020) Authors: Atkinson, Benjamin N.; Steadman, David; Mahy, William; Zhao, Yuguang; Sipthorp, James; Bayle, Elliott D.; Svensson, Fredrik; Papageorgiou, George; Jeganathan, Fiona; Frew, Sarah; Monaghan, Amy; Bictash, Magda; Jones, E. Yvonne; Fish, Paul V. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 3(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗