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You searched for: Author/Creator Feher, Miklos- Feher, Miklos [remove] 2
- 572 2
- Bioorganic chemistry -- Periodicals 2
- Pharmaceutical chemistry -- Periodicals 2
- Ar aryl -- ATP Adenosine-5′-triphosphate -- AUC area under the curve -- BA bioavailability -- CYP Cytochrome P450 -- DBU 1, 8-diazabicyclo[5.4.0]undec-7-ene -- DCM dichloromethane -- DIPEA diisopropylethylamine -- Δ heat -- DME 1, 2-dimethoxyethane -- DMF N, N-dimethylformamide -- DMSO dimethyl sulfoxide -- dppf 1, 1′-bis(diphenylphosphino)ferrocene -- h hour or human (in MS) -- GI50 half maximal cell growth inhibitory concentration -- Hb hydrophobe -- IC50 half maximal inhibitory concentration -- m mouse -- mCPBA meta-chloroperoxybenzoic acid -- μw microwave irradiation -- Mps1 Monopolar spindle protein 1 -- ND not determined -- PDB protein data bank -- PK pharmacokinetics -- pin pinacol -- PMB para-methoxybenzyl -- r rat -- rt room temperature -- SNAr Nucleophilic Aromatic Substitution -- TBTU O-(benzotriazol-1-yl)-N, N, N′, N′-tetramethyluronium tetrafluoroborate -- TFA trifluoroacetic acid -- THF tetrahydrofuran -- THP tetrahydro-2H-pyran -- TTK Tyrosine Threonine Kinase 1
- Polo-like kinase 4 -- PLK4 inhibitors -- Spiro[cyclopropane-1, 3′-indolin]-2′-ones -- (1H-Indazol-6-yl)-methylene)indolin-2-ones -- Antitumor agent 1
- Tyrosine Threonine Kinase (TTK) -- Monopolar spindle 1 kinase (Mps1) -- Antimitotic -- Inhibitor -- Cancer 1