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Author/Creator Fairhurst, Robin A.

1. Approaches to selective fibroblast growth factor receptor 4 inhibition through targeting the ATP-pocket middle-hinge region12. Issue 8 (8th June 2017)

Authors:
Fairhurst, Robin A.; Knoepfel, Thomas; Leblanc, Catherine; Buschmann, Nicole; Gaul, Christoph; Blank, Jutta; Galuba, Inga; Trappe, Jörg; Zou, Chao; Voshol, Johannes; Genick, Christine; Brunet-Lefeuvre, Peggy; Bitsch, Francis; Graus-Porta, Diana; Furet, Pascal
Journal:
MedChemComm
Issue:
Volume 8:Issue 8(2017)
Page Start:
1604
Record Type:
Journal Article
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2. Discovery of a novel tricyclic 4H-thiazolo[5′, 4′:4, 5]pyrano[2, 3-c]pyridine-2-amino scaffold and its application in a PI3Kα inhibitor with high PI3K isoform selectivity and potent cellular activity. Issue 17 (1st September 2015)

Authors:
Gerspacher, Marc; Fairhurst, Robin A.; Mah, Robert; Roehn-Carnemolla, Esther; Furet, Pascal; Fritsch, Christine; Guthy, Daniel A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 17(2015)
Page Start:
3582
Record Type:
Journal Article
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4. Identification and optimisation of 4, 5-dihydrobenzo[1, 2-d:3, 4-d]bisthiazole and 4, 5-dihydrothiazolo[4, 5-h]quinazoline series of selective phosphatidylinositol-3 kinase alpha inhibitors. Issue 17 (1st September 2015)

Authors:
Fairhurst, Robin A.; Gerspacher, Marc; Imbach-Weese, Patricia; Mah, Robert; Caravatti, Giorgio; Furet, Pascal; Fritsch, Christine; Schnell, Christian; Blanz, Joachim; Blasco, Francesca; Desrayaud, Sandrine; Guthy, Daniel A.; Knapp, Mark; Arz, Dorothee; Wirth, Jasmin; Roehn-Carnemolla, Esther; Luu...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 17(2015)
Page Start:
3575
Record Type:
Journal Article
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5. Identification and optimisation of a 4′, 5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors. Issue 17 (1st September 2015)

Authors:
Fairhurst, Robin A.; Imbach-Weese, Patricia; Gerspacher, Marc; Caravatti, Giorgio; Furet, Pascal; Zoller, Thomas; Fritsch, Christine; Haasen, Dorothea; Trappe, Joerg; Guthy, Daniel A.; Arz, Dorothee; Wirth, Jasmin
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 17(2015)
Page Start:
3569
Record Type:
Journal Article
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6. Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors. Issue 19 (1st October 2016)

Authors:
Fairhurst, Robin A.; Caravatti, Giorgio; Guagnano, Vito; Aichholz, Reiner; Blanz, Joachim; Blasco, Francesca; Wipfli, Peter; Fritsch, Christine; Maira, Sauveur-Michel; Schnell, Christian; Seiler, Frank H.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 19(2016)
Page Start:
4729
Record Type:
Journal Article
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7. Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. Issue 8 (15th April 2016)

Authors:
Fairhurst, Robin A.; Marsilje, Thomas H.; Stutz, Stefan; Boos, Andreas; Niklaus, Michel; Chen, Bei; Jiang, Songchun; Lu, Wenshuo; Furet, Pascal; McCarthy, Clive; Stauffer, Frédéric; Guagnano, Vito; Vaupel, Andrea; Michellys, Pierre-Yves; Schnell, Christian; Jeay, Sébastien
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 8(2016)
Page Start:
2057
Record Type:
Journal Article
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