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Author/Creator Elsby, Robert

1. Mechanistic in vitro studies indicate that the clinical drug–drug interactions between protease inhibitors and rosuvastatin are driven by inhibition of intestinal BCRP and hepatic OATP1B1 with minimal contribution from OATP1B3, NTCP and OAT3. Issue 2 (22nd February 2023)

Authors:
Elsby, Robert; Coghlan, Hannah; Edgerton, Jacob; Hodgson, David; Outteridge, Samuel; Atkinson, Hayley
Journal:
Pharmacology research & perspectives
Issue:
Volume 11:Issue 2(2023)
Page Start:
n/a
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

2. Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (MATE) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamine. Issue 5 (21st September 2017)

Authors:
Elsby, Robert; Chidlaw, Stephen; Outteridge, Samuel; Pickering, Sarah; Radcliffe, Amy; Sullivan, Rebecca; Jones, Hayley; Butler, Philip
Journal:
Pharmacology research & perspectives
Issue:
Volume 5:Issue 5(2017)
Page Start:
n/a
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗