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Author/Creator Ebiike, Hirosato

1. Modification of a dihydropyrrolopyrimidine phosphoinositide 3-kinase (PI3K) inhibitor to improve oral bioavailability. Issue 24 (15th December 2015)

Authors:
Kawada, Hatsuo; Ebiike, Hirosato; Tsukazaki, Masao; Yamamoto, Shun; Koyama, Kohei; Nakamura, Mitsuaki; Morikami, Kenji; Yoshinari, Kiyoshi; Yoshida, Miyuki; Ogawa, Kotaro; Shinma, Nobuo; Tsukuda, Takuo; Ohwada, Jun
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 23:Issue 24(2015)
Page Start:
7650
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

2. Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents. Issue 13 (1st July 2016)

Authors:
Kawada, Hatsuo; Ebiike, Hirosato; Tsukazaki, Masao; Yamamoto, Shun; Koyama, Kohei; Nakamura, Mitsuaki; Morikami, Kenji; Yoshinari, Kiyoshi; Yoshida, Miyuki; Ogawa, Kotaro; Shimma, Nobuo; Tsukuda, Takuo; Ohwada, Jun
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 24:Issue 13(2016)
Page Start:
2897
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

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