1. Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 1: Mitigating the genotoxic liability of an aniline metabolite. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Duplessis, Martin; Gagnon, Alexandre; Garneau, Michel; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1135 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Aza follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 1: Mitigating the genotoxic liability of an aniline metabolite. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Duplessis, Martin; Gagnon, Alexandre; Garneau, Michel; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1135 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Discovery, design, and synthesis of indole-based EZH2 inhibitors. Issue 17 (1st September 2015) Authors: Gehling, Victor S.; Vaswani, Rishi G.; Nasveschuk, Christopher G.; Duplessis, Martin; Iyer, Priyadarshini; Balasubramanian, Srividya; Zhao, Feng; Good, Andrew C.; Campbell, Robert; Lee, Christina; Dakin, Les A.; Cook, Andrew S.; Gagnon, Alexandre; Harmange, Jean-Christophe; Audia, James E.; Cummi... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 17(2015) Page Start: 3644 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance. Issue 15 (1st August 2017) Authors: Crawford, Terry D.; Vartanian, Steffan; Côté, Alexandre; Bellon, Steve; Duplessis, Martin; Flynn, E. Megan; Hewitt, Michael; Huang, Hon-Ren; Kiefer, James R.; Murray, Jeremy; Nasveschuk, Christopher G.; Pardo, Eneida; Romero, F. Anthony; Sandy, Peter; Tang, Yong; Taylor, Alexander M.; Tsui, Vicki... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 27:Issue 15(2017) Page Start: 3534 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Deon, Dan; Duplessis, Martin; Fazal, Gulrez; Gagnon, Alexandre; Garneau, Michel; LaPlante, Steven; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1140 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity. Issue 5 (1st March 2015) Authors: Beaulieu, Pierre L.; Bolger, Gordon; Deon, Dan; Duplessis, Martin; Fazal, Gulrez; Gagnon, Alexandre; Garneau, Michel; LaPlante, Steven; Stammers, Timothy; Kukolj, George; Duan, Jianmin Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 5(2015) Page Start: 1140 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗